Monthly Archives: September 2007

Effectiveness of Low-Dose Naltrexone in the Post-Detoxification Treatment of Opioid Dependence.

  J Clin Psychopharmacol. 2007 Oct;27(5):468-474. Related Articles, Links Effectiveness of Low-Dose Naltrexone in the Post-Detoxification Treatment of Opioid Dependence. Mannelli P, Patkar AA, Peindl K, Murray HW, Wu LT, Hubbard R. *Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC; †Brown University, Providence, RI. BACKGROUND:: The clinical use of naltrexone (NTX) in the treatment of opioid dependence has been limited because of poor compliance and inconsistent outcomes. In particular, the therapeutic benefit of extended treatment with NTX after opioid detoxification is … Continue reading

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Turning back the clock: adopting a healthy lifestyle in middle age.

  Am J Med. 2007 Jul;120(7):598-603. Epub 2007 Apr 19. Related Articles, Links Turning back the clock: adopting a healthy lifestyle in middle age. King DE, Mainous AG 3rd, Geesey ME. Department of Family Medicine, Medical University of South Carolina, Charleston, SC 29425, USA. kingde@musc.edu PURPOSE: To determine the frequency of adopting a healthy lifestyle (5 or more fruits and vegetables daily, regular exercise, BMI 18.5-29.9 kg/m2, no current smoking) in a middle-aged cohort, and determine the subsequent rates of cardiovascular disease (CVD) and mortality … Continue reading

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Depressive Symptoms Predict Mucosal Wound Healing.

Psychosom Med. 2007 Aug 31; [Epub ahead of print] Related Articles, Links Depressive Symptoms Predict Mucosal Wound Healing. Bosch JA, Engeland CG, Cacioppo JT, Marucha PT. College of Dentistry (J.A.B., C.G.E., P.T.M.), University of Illinois at Chicago, Chicago, Illinois; School of Sport and Exercise Sciences (J.A.B.), University of Birmingham, Birmingham, UK; Department of Psychology (J.T.C.), University of Chicago, Chicago, Illinois; and Institute for Behavioral Medicine Research (J.A.B., C.G.E., P.T.M.), Ohio State University, Columbus, Ohio. Objective: There is mounting evidence that psychosocial stress can delay wound … Continue reading

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Association between reduced sleep and weight gain in women.

Am J Epidemiol. 2006 Nov 15;164(10):947-54. Epub 2006 Aug 16. Related Articles, Links Association between reduced sleep and weight gain in women. Patel SR, Malhotra A, White DP, Gottlieb DJ, Hu FB. Division of Pulmonary and Critical Care Medicine, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA. srp20@case.edu Physiologic studies suggest that sleep restriction has metabolic effects that predispose to weight gain. The authors investigated the association between self-reported usual sleep duration and subsequent weight gain in the Nurses’ Health Study. … Continue reading

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DSM Biases Evident in Clinical Training and Courtroom Testimony

An important article by Gopal and Bursztajn on the limitations of manual-driven diagnosis (and treatment). It starts: >>The American Psychiatric Association’s Diagnostic and Statistical Manual (DSM),1 which was most recently revised in 2000 with DSM, fourth edition, text revision (DSM-IV- TR), has been helpful in promoting inter-rater reliability or agreement among clinicians. This reliability has been achieved by moving from a causation-heavy, narrative-rich system to a causation-free, narrative- and context-empty system of diagnostic categories. However, as helpful as an increased degree of agreement among clinicians … Continue reading

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Acute exercise reduces the effects of a 35% CO(2) challenge in patients with panic disorder.

J Affect Disord. 2007 Aug 27; [Epub ahead of print] Related Articles, Links Acute exercise reduces the effects of a 35% CO(2) challenge in patients with panic disorder. Esquivel G, Díaz-Galvis J, Schruers K, Berlanga C, Lara-Muñoz C, Griez E. Academic Anxiety Center, Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands. BACKGROUND: Chronic exercise has been shown to have therapeutic effects in panic disorder (PD). The mechanism of these effects is unknown. Acute exercise reduces the effect of a panic challenge in healthy … Continue reading

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