Monthly Archives: January 2008

Hypoxic changes in the central nervous system of noise-exposed mice.

Acta Otolaryngol Suppl. 2007 Oct;(558):73-7.Related Articles, Links Hypoxic changes in the central nervous system of noise-exposedmice. Kim YJ, Kang HH, Ahn JH, Chung JW. Department of Otolaryngology, Pundang Jaesang Hospital, DaeJinMedical Center, Seongnam City, Kyunggi Do, Korea. CONCLUSION: After a noise-induced transient threshold shift,hypoxia occurred in the central nervous system, especially in theauditory cortex, the hippocampus, and the inferior colliculus.OBJECTIVES: Noise-induced inner ear hypoxia was shown by measurementof an increase in hypoxia-inducible factor-1 alpha, which isexpressed? in the nucleus under hypoxic conditions. This study usespimonidazole … Continue reading

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