Monthly Archives: August 2012

Endogenous opioids may protect against minor TBI symptoms

This is an interesting finding. We have shown that people (even “normal” people) with early separation events (early parental divorce, parental loss) have a totally different endogenous opioid reactivity in a challenge test. It would make sense if they therefore were predisposed to more severe TBI and mTBI symptomatology. Morphine protects for head trauma induced cogn… [Neurosci Lett. 2006] – PubMed – NCBI. Abstract: Victims of minor traumatic brain injury (mTBI) can show long lasting cognitive, emotional and concentration difficulties, amnesia, depression, apathy and anxiety. … Continue reading

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Short Sleep May Increase Stroke Risk

This was posted on www.neurologyreviews.com here. SLEEP 2012 MEETING Short Sleep May Increase Stroke Risk 2012;20(7):1,17. BOSTON—Regularly sleeping for less than six hours quadruples the rate of stroke symptoms among middle-aged and older persons with a normal BMI and a low risk of sleep-disordered breathing, according to a study that was presented at the 26th Annual Meeting of the Associated Professional Sleep Societies. Researchers found no association between a six-hour sleep duration and stroke symptoms among overweight and obese persons. Unadjusted results indicated that a … Continue reading

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Inappropriateness of Medication Prescriptions to Elderly Patients in the Primary Care Setting: A Systematic Review

This interesting meta-analysis was just published (notably, in a very reputable open-access, advertisement-free journal). 20% seems a very conservative estimate… The PDF is here: Here is the abstract: RESEARCH ARTICLE Inappropriateness of Medication Prescriptions to Elderly Patients in the Primary Care Setting: A Systematic Review Dedan Opondo1*, Saied Eslami1, Stefan Visscher2, Sophia E. de Rooij3, Robert Verheij2, Joke C. Korevaar2, Ameen Abu-Hanna1 1 Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, 2 Netherlands Institute for Health Services Research (NIVEL), Utrecht, … Continue reading

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SSRIs should be considered in the list of medications that are risk factors for osteoporotic fractures.

Not really news but still an important pharmacovigilance paper. As has been correctly pointed out, relevant to the changing informed consent & decision making landscape. More on the subject matter at http://www.ncbi.nlm.nih.gov/pubmed/17592097 Bone. 2012 Sep;51(3):606-13. Epub 2012 May 30. Antidepressant medications and osteoporosis. Rizzoli R, Cooper C, Reginster JY, Abrahamsen B, Adachi JD, Brandi ML, Bruyère O, Compston J, Ducy P, Ferrari S, Harvey NC, Kanis JA, Karsenty G, Laslop A, Rabenda V, Vestergaard P. Source Division of Bone Diseases, Department of Medical Specialties, Geneva … Continue reading

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From the Blackburn lab: Socioeconomic status and cell aging in children.

I am studying telomerase-environment interactions. Fascinating, as they say. Not news, but –  poverty and lack of education kills (faster), literally. Link http://biochemistry.ucsf.edu/labs/blackburn/index.php?option=com_content&view=article&id=12&Itemid=8 Here is the abstract: Soc Sci Med. 2012 Jun;74(12):1948-51. Epub 2012 Mar 17. Socioeconomic status and cell aging in children. Needham BL, Fernandez JR, Lin J, Epel ES, Blackburn EH. Source Department of Sociology, University of Alabama at Birmingham, 1530 3rd Ave. S., HHB 460C, Birmingham, AL 35294, USA. bneedham@uab.edu Abstract Theory suggests that chronic stress associated with disadvantaged social status may … Continue reading

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Traumatic loss, adult separation anxiety and childhood asthma

Prenatal Stress and Risk of Asthma Hospitalization in the Offspring: A Swedish Population-Based Study Ali S. Khashan, PhD, Susanne Wicks, PhD, Christina Dalman, MD, PhD, Tine B. Henriksen, PhD, Jiong Li, PhD, Preben B. Mortensen, DMSc and Louise C. Kenny, MRCOG, PhD + Author Affiliations From the Anu Research Centre (A.S.K., L.C.K.), Department of Obstetrics and Gynaecology, University College Cork, Cork University Maternity Hospital, Cork, Ireland; Division of Public Health Epidemiology (S.W., C.D.), Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden; and Perinatal Epidemiology … Continue reading

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Unpredictable chronic mild stress and endothelial damage

Just like “mild” traumatic brain injury, mild stress is relative. ___________________________________ Unpredictable Chronic Mild Stress Promotes Atherosclerosis in High Cholesterol–Fed Rabbits Xiao-Ting Lu, PhD, Yun-Fang Liu, PhD, Lei Zhang, PhD, Rui-Xue Yang, PhD, Xiao-Qiong Liu, PhD, Fang-Fang Yan, PhD, Ying-Bin Wang, PhD, Wen-Wu Bai, PhD, Yu-Xia Zhao, MD and Fan Jiang, PhD + Author Affiliations From the Key Laboratory of Cardiovascular Remodeling and Function Research (Chinese Ministry of Education and Chinese Ministry of Health) (X.-T.L., L.Z., F.J.), Departments of Traditional Chinese Medicine (X.-T.L., X.-Q.L., F.-F.Y., … Continue reading

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A panic mimic?

Cardiovascular Morbidity and Mortality in Finnish Men and Women Separated Temporarily From Their Parents in Childhood—A Life Course Study Hanna Alastalo, MHS, Katri Räikkönen, PhD, Anu-Katriina Pesonen, PhD, Clive Osmond, PhD, David J.P. Barker, MD, Kati Heinonen, PhD, Eero Kajantie, MD, PhD and Johan G. Eriksson, MD, DMSc, PhD + Author Affiliations From the Department of Chronic Disease Prevention (H.A., E.K., J.G.E.), National Institute for Health and Welfare; Department of Public Health (H.A.),Hjelt Institute, Institute of Behavioural Sciences (K.R., A.-K.P., K.H.), Department of General Practice … Continue reading

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To what extent is mortality predictable from facial photographs?

Nifty paper on the predictive validity of the impression of “old age”. Here is the abstract: __________________________________________ Predicting Mortality From Human Faces Dominika Dykiert, PhD, Timothy C. Bates, PhD, Alan J. Gow, PhD, Lars Penke, PhD, John M. Starr, MA, FRCPE and Ian J. Deary, PhD, FRCPE + Author Affiliations From the Centre for Cognitive Ageing and Cognitive Epidemiology (D.D., T.C.B., A.J.G., L.P., J.M.S., I.J.D.), Department of Psychology (D.D., T.C.B., A.J.G., L.P., I.J.D.), and Geriatric Medicine Unit (J.M.S.), University of Edinburgh, Edinburgh, United Kingdom. Address … Continue reading

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the psychiatryneurology.net – legal

I created a new e-newspaper, the psychiatryneurology.net – legal, a digest of legal news related to medical tort, traumatic brain injury, psychological trauma and related topics. Looks beautiful. Hard not to love technology. Please subscribe. Link http://paper.li/DrMauricePreter/1343869858  

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