Monthly Archives: July 2013

Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial.

Phytother Res. 2013 Jul 6. doi: 10.1002/ptr.5025. [Epub ahead of print] Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial. Sanmukhani J, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB. Source Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat, India. Abstract Curcumin, an active ingredient of Curcuma longa Linn (Zingiberaceae), has shown potential antidepressant-like activity in animal studies. The objectives of this trial were to compare the efficacy and safety of curcumin with fluoxetine in … Continue reading

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Medication & Health Insurance Resources

Excellent resource by Ken Pope, PhD. Resources for Finding Low-Cost Health Insurance & Lowest-Cost Medications Ken Pope, Ph.D., ABPP Some of you may know of clients, relatives, or friends who are having difficulty finding health insurance or affording needed medications, perhaps using smaller doses or going without because their resources are needed for rent, etc. I’ve gathered names, brief descriptions, and links to sites that can be helpful in locating the lowest price for a particular medication — available either online or at the pharmacies … Continue reading

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Piperine and curcumin exhibit synergism in attenuating D-galactose induced senescence in rats.

Piperine and curcumin exhibit synergism in attenuating D-galactose induced senescence in rats. Banji D, Banji OJ, Dasaroju S, Annamalai AR. Source Department of Pharmacology, Nalanda College of Pharmacy, Charlapally, Nalgonda 508001, A.P., India. davidbanji@gmail.com Abstract Aging is associated with progressive decline in mental abilities and functional capacities. Postmitotic tissues are most vulnerable to alteration due to oxidative damage leading to behavioral and biochemical changes. We hypothesized that the anatomical and functional facets of the brain could be protected with powerful antioxidants such as piperine and … Continue reading

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Identification of candidate IgG biomarkers for Alzheimer’s disease via combinatorial library screening.

This is important news. Cell. 2011 Jan 7;144(1):132-42. doi: 10.1016/j.cell.2010.11.054. Identification of candidate IgG biomarkers for Alzheimer’s disease via combinatorial library screening. Reddy MM, Wilson R, Wilson J, Connell S, Gocke A, Hynan L, German D, Kodadek T. Source Opko Health Laboratories, Jupiter, FL 33458, USA. Abstract The adaptive immune system is thought to be a rich source of protein biomarkers, but diagnostically useful antibodies remain unknown for a large number of diseases. This is, in part, because the antigens that trigger an immune response … Continue reading

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Calorie restriction: what recent results suggest for the future of ageing research.

Eur J Clin Invest. 2010 May;40(5):440-50. doi: 10.1111/j.1365-2362.2010.02276.x. Calorie restriction: what recent results suggest for the future of ageing research. Smith DL Jr, Nagy TR, Allison DB. Source Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA. dsmithjr@uab.edu Abstract BACKGROUND: Calorie Restriction (CR) research has expanded rapidly over the past few decades and CR remains the most highly reproducible, environmental intervention to improve health and extend lifespan in animal studies. Although many model organisms have consistently demonstrated positive responses to CR, … Continue reading

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The promise of dietary restriction mimetics in healthy aging

Biofactors. 2010 Sep-Oct;36(5):377-82. doi: 10.1002/biof.127. Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging. Mouchiroud L, Molin L, Dallière N, Solari F. Source UMR, CNRS Université Lyon, Centre Léon Bérard, France. Abstract Life expectancy at the turn of the 20th century was 46 years on average worldwide and it is around 65 years today. The correlative increase in age-associated diseases incidence has a profound public health impact and is an important matter of concern for our … Continue reading

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Traumatic brain injury may be an independent risk factor for stroke

Traumatic brain injury may be an independent risk factor for stroke James F. Burke, MD, MS, Jessica L. Stulc, MD, MPH, Lesli E. Skolarus, MD, MS, Erika D. Sears, MD, MS, Darin B. Zahuranec, MD, MS and Lewis B. Morgenstern, MD +Show Affiliations | + Show Full Disclosures Correspondence to Dr. Burke: jamesbur@umich.edu Published online before print June 26, 2013, doi: 10.1212/WNL.0b013e318297eecf Neurology July 2, 2013 vol. 81 no. 1 33-39 Abstract Full Text Full Text (PDF) Also available: Figures Only PPT Slides of All … Continue reading

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