Yearly Archives: 2016

Update on the treatment of Alzheimer’s Disease – from the International Conference of Parkinson Disease & Movement Disorders/MDS Developing World Education Program (DWEP). Shanghai First People’s Hospital, Jiao Tong University, Shanghai, PRC. September 30, 2016

Update on the treatment of Alzheimer’s Disease – from the International Conference of Parkinson Disease & Movement Disorders/MDS Developing World Education Program (DWEP). Shanghai First People’s Hospital, Jiao Tong University, Shanghai, PRC. September 30, 2016 Continue reading

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Brain atrophy is already evident in patients with pre diabetes – The Maastricht Study

Key clinical point: People with prediabetes and type 2 diabetes have more white matter hyperintensities and lower white matter volume than do those with healthy glucose metabolism.

Major finding: Healthy subjects carried about 0.75 mL of white matter hyperintensities, while prediabetic subjects carried about 1.25 mL, and those with diabetes, about 2.0 mL.

Data source: The subset of the Maastricht Study comprised 2,251 subjects.

Disclosures: Dr. van Agtmaal had no financial disclosures. Continue reading

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Multimodal randomized Functional MR imaging of the effects of Methylene Blue in the human Brain

Multimodal randomized Functional MR imaging of the effects of Methylene Blue in the human Brain A new treatment for short-term memory loss? Or radiological gadgetry? Purpose To investigate the sustained-attention and memory-enhancing neural correlates of the oral administration of methylene blue in the healthy human brain. Materials and Methods The institutional review board approved this prospective, HIPAA-compliant, randomized, double-blinded, placebo-controlled clinical trial, and all patients provided informed consent. Twenty-six subjects (age range, 22–62 years) were enrolled. Functional magnetic resonance (MR) imaging was performed with a … Continue reading

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Arthritis and suicide attempts: findings from a large nationally representative Canadian survey

Arthritis and suicide attempts: findings from a large nationally representative Canadian survey The objectives of this study were (1) to determine the odds of suicide attempts among those with arthritis compared with those without and to see what factors attenuate this association and (2) to identify which factors are associated with suicide attempts among adults with arthritis. Secondary data analysis of the nationally representative 2012 Canadian Community Health Survey-Mental Health (CCHS-MH) was performed. For objective 1, those with and without arthritis were included (n = 21,744). For … Continue reading

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Just Published: Panic Disorder: Neurobiological and Treatment Aspects 1st ed. 2016 Edition

I am very pleased that this interesting collaborative project has come to fruition. Great introductory chapter by Nardi and Freire, numerous excellent contributions, and a recap of our panic theory and data showing that early childhood loss causes permanent changes in the endogenous opioid system of asymptomatic, clinically healthy adults. Continue reading

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Periodontitis and Cognitive Decline in Alzheimer’s Disease

Periodontitis and Cognitive Decline in Alzheimer’s Disease Continue reading

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Secret Ingredients: Who Knows What’s in Your Food?

  Secret Ingredients: Who Knows What’s in Your Food? http://tinyurl.com/zwu7895 Wendee Nicole Wendee Nicole, based in Houston, TX, has written for Nature, Scientific American, National Wildlife, and other magazines.   British chef and food activist Jamie Oliver ignited a firestorm in January 2011 when he mentioned on theLate Show with David Letterman that castoreum, a substance used to augment some strawberry and vanilla flavorings, comes from what he described as “rendered beaver anal gland.”1 The next year, vegans were outraged to learn that Starbucks used … Continue reading

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Can Herpes Cause Alzheimer’s Disease?

  Can Herpes Cause Alzheimer’s Disease? http://tinyurl.com/gr4fqab Itzhaki, Ruth F.a; * | Lathe, Richardb | Balin, Brian J.c | Ball, Melvyn J.d | Bearer, Elaine L.e | Braak, Heikof | Bullido, Maria J.g | Carter, Chrish | Clerici, Marioi | Cosby, S. Louisej | Del Tredici, Kellyf | Field, Hughk | Fulop, Tamasl | Grassi, Claudiom | Griffin, W. Sue T.n | Haas, Jürgenb | Hudson, Alan P.o | Kamer, Angela R.p | Kell, Douglas B.q | Licastro, Federicor | Letenneur, Lucs | Lövheim, Hugot … Continue reading

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Whole-body PET/CT scanning is accompanied by substantial radiation dose and cancer risk.

Whole-body PET/CT scanning is accompanied by substantial radiation dose and cancer risk. http://tinyurl.com/h6vzzns Huang B1, Law MW, Khong PL. 1Department of Diagnostic Radiology, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Rd, Room 406, Block K, Hong Kong. Abstract PURPOSE: To estimate the radiation dose from whole-body fluorine 18 ((18)F)-fluorodeoxyglucose (FDG) positron emission tomographic (PET)/computed tomographic (CT) studies and to evaluate the induced cancer risk to U.S. and Hong Kong populations. MATERIALS AND METHODS: Fluorine 18-FDG PET/CT studies obtained by using a 64-detector CT … Continue reading

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Genetic Radiation Risks-A Neglected Topic in the Low Dose

Genetic Radiation Risks-A Neglected Topic in the Low Dose http://tinyurl.com/zosu2v8 Busby C1, Schmitz-Feuerhake I2, Pflugbeil S3. 1Environmental Research SIA, Riga, Latvia. 2University of Bremen, Bremen, Germany. 3German Society for Radiation Protection, Berlin, Germany. Abstract The committee of the United Nations for the Evaluation of Radiation Effects UNSCEAR as well as the International Commission on Radiological Protection ICRP up to now have derived a very low risk for hereditary diseases in humans from experiments in mice. They claim that there are no human data to refer … Continue reading

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Glycemic Index (GI), Glycemic Load (GL) and Lung Cancer Risk

Glycemic Index (GI), Glycemic Load (GL) and Lung Cancer Risk http://tinyurl.com/jq5hmqq Stephanie C. Melkonian1, Carrie R. Daniel1, Yuanqing Ye1, Jeanne A. Pierzynski1, Jack A. Roth2, and Xifeng Wu1,*, 1Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 2Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas. ↵*Corresponding Author: Xifeng Wu, Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Unit 1340, 1155 Pressler Boulevard, Houston, TX 77030. Phone: 713-745-2485; Fax: 713-792-4657; E-mail: … Continue reading

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Significant Associations with the Inflammation Biomarkers for age, BMI, Dietary Saturated fat, and EPA+DHA Omega-3 fatty acids

Significant Associations with the Inflammation Biomarkers for age, BMI, Dietary Saturated fat, and EPA+DHA Omega-3 fatty acids http://tinyurl.com/hyjq6hn Sandi L. Navarro1,*, Elizabeth D. Kantor1,2, Xiaoling Song1, Ginger L. Milne3, Johanna W. Lampe1, Mario Kratz1, and Emily White1 1Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Washington. 2Memorial Sloan Kettering Cancer Center, Department of Epidemiology and Biostatistics, New York, New York. 3Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee. ↵*Corresponding Author: Sandi L. Navarro, Fred Hutchinson Cancer Research Center, 1100 … Continue reading

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