Category Archives: Complementary – Alternative Medicine

BMJ.org: Research News Benzodiazepines may be linked to Alzheimer’s disease, study finds

Research News Benzodiazepines may be linked to Alzheimer’s disease, study finds BMJ 2014; 349 doi: http://dx.doi.org/10.1136/bmj.g5555 (Published 10 September 2014)Cite this as: BMJ 2014;349:g5555 Article Related content Metrics Responses Get access to this article and to all of thebmj.com for 14 days. Sign up today for a 14 day free trial. Access to the full version of this article requires a subscription payment. Please login or subscribe below. Zosia Kmietowicz Author affiliations Taking benzodiazepines is associated with an increased risk of developing Alzheimer’s disease, particularly in long term users, a study has … Continue reading

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Neurology.org: Poor sleep quality is associated with increased cortical atrophy in community-dwelling adults

Sleep and cognitive status is a developing hot topic. When will hospitals have to assure a peaceful, uninterrupted night for inpatients? Poor sleep quality is associated with increased cortical atrophy in community-dwelling adults Claire E. Sexton, DPhil, Andreas B. Storsve, MSc, Kristine B. Walhovd, PhD, Heidi Johansen-Berg, DPhil and Anders M. Fjell, PhD +SHOW AFFILIATIONS | + SHOW FULL DISCLOSURES Correspondence to Dr. Sexton: claire.sexton@ndcn.ox.ac.uk Published online before print September 3, 2014, doi: 10.1212/WNL.0000000000000774Neurology September 9, 2014 vol. 83 no. 11 967-973 Abstract Full Text Full Text (PDF) Also available: Figures Only Data Supplement … Continue reading

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Neurology.org: Vitamin D and the risk of dementia and Alzheimer disease

Our results confirm that vitamin D deficiency is associated with a substantially increased risk of all-cause dementia and Alzheimer disease. This adds to the ongoing debate about the role of vitamin D in nonskeletal conditions. Continue reading

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Use of bilateral mastectomy increased significantly throughout California from 1998 through 2011 and was not associated with lower mortality than that achieved with breast-conserving surgery plus radiation.

September 2014, Vol 312, No. 9 > < Previous ArticleNext Article > Original Investigation | September 3, 2014 Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011 FREE Allison W. Kurian, MD, MSc1,2; Daphne Y. Lichtensztajn, MD, MPH3; Theresa H. M. Keegan, PhD2,3; David O. Nelson, PhD2,3; Christina A. Clarke, PhD2,3; Scarlett L. Gomez, PhD2,3 [+] Author Affiliations JAMA. 2014;312(9):902-914. doi:10.1001/jama.2014.10707. Text Size: A A A Article Figures Tables Supplemental Content References ABSTRACT ABSTRACT | INTRODUCTION | METHODS | RESULTS | DISCUSSION | CONCLUSIONS |ARTICLE INFORMATION | REFERENCES Importance  Bilateral mastectomy is increasingly used to treat unilateral breast cancer. Because it may have medical and psychosocial complications, a better understanding of its use and … Continue reading

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Metabolic features of the cell danger response. [Mitochondrion. 2013] – PubMed – NCBI

This is a really exciting integrative paper on the (clinically and heuristically relevant) hot topic du jour: Inflammation.  I came across it when I was researching Tourette’s syndrome and inflammation – am seeing increasing numbers of patients without a good explanation for their symptom exacerbation, with respiratory disease and low Vitamin D levels. Mitochondrion. 2013 Aug 24. pii: S1567-7249(13)00239-0. doi: 10.1016/j.mito.2013.08.006. [Epub ahead of print] Metabolic features of the cell danger response. Naviaux RK. Author information Abstract The cell danger response (CDR) is the evolutionarily … Continue reading

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Exercise’s Psychological & Physical Effects on Health, Disorders, & Quality of Life

Meta-Analyses: Exercise’s Psychological & Physical Effects on Health, Disorders, & Quality of Life. Another gem from Dr. Ken Pope’s web site.    

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Simvastatin impairs exercise training adaptations.

Simvastatin impairs exercise training adaptations. Mikus CR, et al. Show all J Am Coll Cardiol. 2013 Aug 20;62(8):709-14. doi: 10.1016/j.jacc.2013.02.074. Epub 2013 Apr 10. Affiliation Division of Cardiology, Duke University Medical Center, Durham, North Carolina. Abstract OBJECTIVES: This study sought to determine if simvastatin impairs exercise training adaptations. BACKGROUND: Statins are commonly prescribed in combination with therapeutic lifestyle changes, including exercise, to reduce cardiovascular disease risk in patients with metabolic syndrome. Statin use has been linked to skeletal muscle myopathy and impaired mitochondrial function, but … Continue reading

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Long-term use of statins may be associated with increased risks of both ductal and lobular breast cancer among women 55-74 years of age

Search Home PDF Current Issue Past Issues OnlineFirst Long-term statin use and risk of ductal and lobular breast cancer among women 55-74 years of age  Authors Abstract Background: Mechanistic studies largely support the chemopreventive potential of statins. However, results of epidemiologic studies investigating statin use and breast cancer risk have been inconsistent and lacked the ability to evaluate long-term statin use. Methods: We utilized data from a population-based case-control study of breast cancer conducted in the Seattle-Puget Sound region to investigate the relationship between long-term … Continue reading

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Tea drinking and cognitive function in oldest-old Chinese.

J Nutr Health Aging. 2012;16(9):754-8. doi: 10.1007/s12603-012-0077-1. Tea drinking and cognitive function in oldest-old Chinese. Feng L, Li J, Ng TP, Lee TS, Kua EH, Zeng Y. Source Department of Psychological Medicine, National University of Singapore. pcmfl@nus.edu.sg Abstract OBJECTIVE: We examined the longitudinal association between tea drinking frequency and cognitive function in a large sample of oldest-old Chinese. DESIGN: population-based longitudinal cohort study. SETTING: The Chinese Longitudinal Healthy Longevity Survey (CLHLS). PARTICIPANTS: 7139 participants aged 80 to 115 (mean age 91.4 years) who provided complete … Continue reading

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Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial.

Phytother Res. 2013 Jul 6. doi: 10.1002/ptr.5025. [Epub ahead of print] Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial. Sanmukhani J, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB. Source Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat, India. Abstract Curcumin, an active ingredient of Curcuma longa Linn (Zingiberaceae), has shown potential antidepressant-like activity in animal studies. The objectives of this trial were to compare the efficacy and safety of curcumin with fluoxetine in … Continue reading

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Piperine and curcumin exhibit synergism in attenuating D-galactose induced senescence in rats.

Piperine and curcumin exhibit synergism in attenuating D-galactose induced senescence in rats. Banji D, Banji OJ, Dasaroju S, Annamalai AR. Source Department of Pharmacology, Nalanda College of Pharmacy, Charlapally, Nalgonda 508001, A.P., India. davidbanji@gmail.com Abstract Aging is associated with progressive decline in mental abilities and functional capacities. Postmitotic tissues are most vulnerable to alteration due to oxidative damage leading to behavioral and biochemical changes. We hypothesized that the anatomical and functional facets of the brain could be protected with powerful antioxidants such as piperine and … Continue reading

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Calorie restriction: what recent results suggest for the future of ageing research.

Eur J Clin Invest. 2010 May;40(5):440-50. doi: 10.1111/j.1365-2362.2010.02276.x. Calorie restriction: what recent results suggest for the future of ageing research. Smith DL Jr, Nagy TR, Allison DB. Source Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA. dsmithjr@uab.edu Abstract BACKGROUND: Calorie Restriction (CR) research has expanded rapidly over the past few decades and CR remains the most highly reproducible, environmental intervention to improve health and extend lifespan in animal studies. Although many model organisms have consistently demonstrated positive responses to CR, … Continue reading

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