Category Archives: Uncategorized

Metabolic features of the cell danger response. [Mitochondrion. 2013] – PubMed – NCBI

This is a really exciting integrative paper on the (clinically and heuristically relevant) hot topic du jour: Inflammation.  I came across it when I was researching Tourette’s syndrome and inflammation – am seeing increasing numbers of patients without a good explanation for their symptom exacerbation, with respiratory disease and low Vitamin D levels. Mitochondrion. 2013 Aug 24. pii: S1567-7249(13)00239-0. doi: 10.1016/j.mito.2013.08.006. [Epub ahead of print] Metabolic features of the cell danger response. Naviaux RK. Author information Abstract The cell danger response (CDR) is the evolutionarily … Continue reading

Posted in Complementary - Alternative Medicine, dietary, epigenetics, Events, Fifth Avenue Concierge Medicine, Health, new treatments, News, Psychiatry/Neurology, Uncategorized | Tagged , , , , | Comments Off on Metabolic features of the cell danger response. [Mitochondrion. 2013] – PubMed – NCBI

The top online health services for consumers | VentureBeat | Health | by Christina Farr

Interesting line-up of online medical shopping/info sites. Some might offer some relief from/price-conscious alternatives to emergency room visits. Perhaps good news for U.S. patients facing gigantic out-of-pocket expenses for not-sure-what value-add, a worldwide market for digital medical tourism for low-complexity medical care is emerging (see for instance, here https://ring.md/) On the other hand, I don’t see how these digital med-tech sites can replace (i.e., provide relief for the increasingly felt absence of ) expertise-through-experience based doctoring, with true, trust-based, long-term doctor-patient rapport. The top online … Continue reading

Posted in Events, Fifth Avenue Concierge Medicine, Health, News, Uncategorized | Tagged , | Comments Off on The top online health services for consumers | VentureBeat | Health | by Christina Farr

A senior executive with Britain’s biggest drugs company has admitted that most prescription medicines do not work on most people who take them. Science – News – The Independent

I just had the great pleasure of meeting Allen Roses. The 2003 article quoted is a reminder of “plus ca change, plus c’est la meme chose”. Glaxo chief: Our drugs do not work on most patients – Science – News – The Independent.    

Posted in epigenetics, Events, Fifth Avenue Concierge Medicine, Forensic Neuropsychiatry, Psychiatry/Neurology, Uncategorized | Tagged , , | Comments Off on A senior executive with Britain’s biggest drugs company has admitted that most prescription medicines do not work on most people who take them. Science – News – The Independent

DSM-5 focuses on drugs, not talk therapy

DSM-5 focuses on drugs, not talk therapy A well-written and thoughtful op-ed in the Philadelphia Inquirer by a social worker and psychotherapist. Please also re-read my post on expanding illness definitions.

Posted in Affective Neuroscience, Fifth Avenue Concierge Medicine, Forensic Neuropsychiatry, Health, News, Psychiatry/Neurology, Uncategorized | Comments Off on DSM-5 focuses on drugs, not talk therapy

Invitation to my Grand Rounds Talk at Mount Sinai, Wednesday, October 9, 2013, 8am

Please join us for our next Neurology Grand Rounds on Wednesday, October 9th at 8 AM in Davis Auditorium (Hess Center for Science and Medicine) at 1470 Madison Ave between 101st and 102nd streets. Refreshments will be served at 7:30 AM so please feel free to arrive early.

Title: “Panic, Separation Anxiety, Suffocation False Alarms and Endogenous Opioids: Can panic research inform clinical neurology?”

Presenter: Dr. Maurice Preter, MD
Assistant Professor of Clinical Psychiatry,
Columbia’s College of Physicians and Surgeons;
Associate Professor of Neurology (Adj.),
SUNY Downstate Medical Center, Brooklyn, NY
Continue reading

Posted in Affective Neuroscience, China, Events, Fifth Avenue Concierge Medicine, Health, News, Psychiatry/Neurology, Uncategorized | Tagged , , , , , , , , , , , , | Comments Off on Invitation to my Grand Rounds Talk at Mount Sinai, Wednesday, October 9, 2013, 8am

Could not resist posting this ad I found in a local NYC Japanese magazine.  

Posted on by MP | Comments Off on Homeopathic Shochu production?

Acquired synesthesia?

I came across this interesting article Colizoli O, Murre JM, and Rouw R (2012). Pseudo-Synesthesia through Reading Books with Colored Letters. PloS one, 7 (6) PMID: 22761905 posted at http://neuroskeptic.blogspot.com/2012/07/can-you-learn-to-be-synaesthetic.html I agree with the blogger and some real syn-esthetics who commented that it really has little to do with synesthesia, and more with mnemotechnic. I wonder if it could be used to learn Chinese characters.    

Posted in China, language, News, Psychiatry/Neurology, Uncategorized | Comments Off on Acquired synesthesia?

Pro- and anti-inflammatory cytokines expression in rat’s brain and spleen exposed to chronic mild stress: involvement in depression.

Behav Brain Res. 2011 Nov 20;225(1):135-41. Epub 2011 Jul 8.Pro- and anti-inflammatory cytokines expression in rat’s brain and spleen exposed to chronic mild stress: involvement in depression.You Z, Luo C, Zhang W, Chen Y, He J, Zhao Q, Zuo R, Wu Y.Source Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China. youzili@uestc.edu.cnAbstract The association between pro-inflammatory cytokines and depression has been reported by many studies. However, the mechanisms by … Continue reading

Posted in Uncategorized | Tagged | Comments Off on Pro- and anti-inflammatory cytokines expression in rat’s brain and spleen exposed to chronic mild stress: involvement in depression.

Relationship between inflammation and cognitive function in obstructive sleep apnea.

Sleep Breath. 2009 Mar;13(1):35-41. Epub 2008 Jun 13.Relationship between inflammation and cognitive function in obstructive sleep apnea.Haensel A, Bardwell WA, Mills PJ, Loredo JS, Ancoli-Israel S, Morgan EE, Heaton RK, Dimsdale JE.Source Department of General Internal Medicine, University Hospital Berne, Berne, Switzerland.AbstractOBJECTIVES: Obstructive sleep apnea (OSA) can have adverse effects on cognitive functioning, mood, and cardiovascular functioning. OSA brings with it disturbances in sleep architecture, oxygenation, sympathetic nervous system function, and inflammatory processes. It is not clear which of these mechanisms is linked to the … Continue reading

Posted in Uncategorized | Tagged , | Comments Off on Relationship between inflammation and cognitive function in obstructive sleep apnea.

Substance P at the nexus of mind and body in chronic inflammation and affective disorders.

Reductionistic but still of interest. Psychol Bull. 2007 Nov;133(6):1007-37.Substance P at the nexus of mind and body in chronic inflammation and affective disorders.Rosenkranz MA.Source Department of Psychology, University of Wisconsin-Madison, WI 53705, USA. marosenk@wisc.eduAbstract For decades, research has demonstrated that chronic diseases characterized by dysregulation of inflammation are particularly susceptible to exacerbation by stress and emotion. Likewise, rates of depression and anxiety are overrepresented in individuals suffering from chronic inflammatory disease. In recent years, substance P has been implicated in both the pathophysiology of inflammatory … Continue reading

Posted in Uncategorized | Tagged | Comments Off on Substance P at the nexus of mind and body in chronic inflammation and affective disorders.

Effects of seasonal mood changes on seasonal variations in coronary heart disease: role of immune system, infection, and inflammation.

Nice piece by Leo Sher from before the Vitamin D connection was on everyone’s mind. Med Hypotheses. 2001 Jan;56(1):104-6.Effects of seasonal mood changes on seasonal variations in coronary heart disease: role of immune system, infection, and inflammation.Sher L.Abstract Coronary heart disease shows a winter peak and summer trough in incidence and mortality. A substantial part of a general population experiences seasonal mood changes including winter depression. Many studies demonstrate that depression is associated with increased incidence, morbidity, and mortality of cardiovascular disease. Therefore, the author … Continue reading

Posted in Uncategorized | Tagged | Comments Off on Effects of seasonal mood changes on seasonal variations in coronary heart disease: role of immune system, infection, and inflammation.

Should I Resign From the American Psychiatric Association? – Psychiatric Times

Should I Resign From the American Psychiatric Association? – Psychiatric Times

Posted in Uncategorized | Comments Off on Should I Resign From the American Psychiatric Association? – Psychiatric Times