Tag Archives: adverse childhood events

Panic Attacks and Panic Disorder – what is it and how can it be treated?

Panic Attacks and Panic Disorder – what is it and how can it be treated? Continue reading

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Alzheimer’s Disease – what is it and how can it be treated?

Alzheimer’s Disease – what is it and how can it be treated? Continue reading

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Arthritis and suicide attempts: findings from a large nationally representative Canadian survey

Arthritis and suicide attempts: findings from a large nationally representative Canadian survey The objectives of this study were (1) to determine the odds of suicide attempts among those with arthritis compared with those without and to see what factors attenuate this association and (2) to identify which factors are associated with suicide attempts among adults with arthritis. Secondary data analysis of the nationally representative 2012 Canadian Community Health Survey-Mental Health (CCHS-MH) was performed. For objective 1, those with and without arthritis were included (n = 21,744). For … Continue reading

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Stress resilience and subsequent risk of type 2 diabetes in 1.5 million young men

  http://link.springer.com/article/10.1007/s00125-015-3846-7 Stress resilience and subsequent risk of type 2 diabetes in 1.5 million young men Casey Crump  , Jan Sundquist , Marilyn A. Winkleby , Kristina Sundquist $39.95 / €34.95 / £29.95 * * Final gross prices may vary according to local VAT. Get Access Abstract Aims/hypothesis Psychosocial stress in adulthood is associated with a higher risk of type 2 diabetes, possibly mediated by behavioural and physiological factors. However, it is unknown whether low stress resilience earlier in life is related to subsequent development of type 2 diabetes. We examined whether low … Continue reading

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Preter Klein Panic disorder theory now available on PubMed Central (PMC)

[nihms] Manuscript #585187: Your manuscript is available in PMC Dear Maurice Preter, Manuscript NIHMS585187 (“Lifelong opioidergic vulnerability through early life separation: A recent extension of the false suffocation alarm theory of panic disorder”) has been loaded into PubMed Central (PMC) and made available for public access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195810 The submission process for this manuscript is now complete. We encourage you to make further manuscript submissions as they become eligible. As always, please feel free to contact the NIHMS Help Desk with any questions at http://www.nihms.nih.gov/db/sub.cgi?page=email. Thank you … Continue reading

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Special issue on panic disorder: Actual separations and losses during childhood, such parental death, parental separation or divorce (CPL), effect lifelong alterations in the physiological reactivity of the endogenous opioid system of healthy adults.

This is the final, published version of our paper, published in the special issue of Neuroscience & Biobehavioral Reviews Volume 46, Part 3, October 2014, Pages 345–351 Translational approaches to panic disorder http://www.sciencedirect.com/science/article/pii/S0149763414000827 PDF: Preter Klein 2014 final journal version Nov 20 2014  FULLTEXT:  Article outline Highlights Abstract Keywords 1. Panic and comorbid conditions 2. Testing the panic-suffocation-false alarm-endogenous opioid connection References Neuroscience & Biobehavioral Reviews Volume 46, Part 3, October 2014, Pages 345–351 Translational approaches to panic disorder Review Lifelong opioidergic vulnerability through early life … Continue reading

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Autoimmune disease, inflammation and the brain

Went to a fabulous lecture by  Dr. Souhel Najjar on autoimmune encephalitis this morning. As a reminder, bad relationships (including with one’s self-image etc.) can also cause/contribute to inflammatory burden. Below is a well-informed and written piece on Anti-NMDA-receptor encephalitis (one of many), courtesy of Wikipedia. Last edited 11 days ago by an anonymous user Anti-NMDA receptor encephalitis Watch this page Anti-NMDA (N-methyl D-aspartate) receptor antibody encephalitis, also termed NMDA receptor antibody encephalitis, is an acute form of encephalitis which is potentially lethal but has high probability for … Continue reading

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The relationship between childhood parental loss and metabolic syndrome in obese subjects.

Pro-inflammatory effects of CPL? [M]ultivariate logistic regression analysis revealed that both childhood loss of a parent and a body mass index (BMI) value greater than 50 were significant predictors of metabolic syndrome. This study provides preliminary evidence linking childhood parental loss to risk factors for the development of metabolic syndrome. Continue reading

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Association of Childhood Adversities and Early-Onset Mental Disorders With Adult-Onset Chronic Physical Conditions

Important paper on childhood adversities an adult-age chronic medical conditions, published just before our study on endogenous opioid dysregulation after early childhood adversity in psychiatrically and physically “healthy” adults.   Archives of General Psychiatry August 2011, Vol 68, No. 8 > < Previous ArticleNext Article > Original Article | Aug 2011 Association of Childhood Adversities and Early-Onset Mental Disorders With Adult-Onset Chronic Physical Conditions Kate M. Scott, PhD; Michael Von Korff, ScD; Matthias C. Angermeyer, MD, PhD; Corina Benjet, PhD; Ronny Bruffaerts, PhD; Giovanni de Girolamo, MD; Josep Maria Haro, MD, MPH, … Continue reading

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Bread, pasta and a sedentary lifestyle – will they require disclaimers? Diabetologia: Prediabetes is associated with an increased risk of cancer.

Data from 891,426 participants were derived from 16 prospective cohort studies. Prediabetes was associated with an increased risk of cancer overall (RR 1.15; 95% CI 1.06, 1.23). Continue reading

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N. Szajnberg, MD on “Lifelong opioidergic vulnerability through early life separation”

Bowlby was a careful observer. His entire volume on Loss spoke to the power of early childhood adversity and later life. More recently, a pediatric nephrologist at Kaiser in collaboration with others has shown that early childhood adversities, including loss, results in later adulthood medical ailments (Filetti et al); and Szajnberg and Massie followed Brodie’s cohort at thirty years to demonstrate this clinically.

Yet, Preter and Klein, citing the work of others, have shown pharmacological evidence of what appears to be a lifelong disorder in opiodergic systems due to childhood loss. Continue reading

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Coronary Heart Disease: Psychological Aspects

Psychological Aspects of Coronary Heart Disease: 126 Studies Published in 2012-2014 Another useful resource provided by the page of Kenneth S. Pope, Ph.D. ABPP, including gems like: Vlachaki, C. and K. Maridaki Kassotaki (2013). “Coronary heart disease and emotional intelligence.” Glob J Health Sci 5(6): 156-165.

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