‘On-Demand’ Fast Mobilizes Fat; Low-Carb Breakfast Stymies Hunger – Medscape – Oct 12, 2020.

‘On-Demand’ Fast Mobilizes Fat; Low-Carb Breakfast Stymies Hunger – Medscape – Oct 12, 2020.   ‘On-Demand’ Fast Mobilizes Fat; Low-Carb Breakfast Stymies Hunger Becky McCall October 12, 2020 Greater fat tissue mobilization can be achieved through early-day fasting in comparison to consuming a low-carbohydrate breakfast or a Mediterranean-style … Continue reading

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Does the ε2 allele remain protective against β-amyloid (Aβ) accumulation in the presence of the ε4 allele?

Does the ε2 allele remain protective against β-amyloid (Aβ) accumulation in the presence of the ε4 allele? Yes, but so does good sleep, low HbA1c, low anxiety, low inflammation etc. Association Between Apolipoprotein E ε2 vs ε4, Age, and β-Amyloid … Continue reading

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Metformin Use Is Associated With Slowed Cognitive Decline and Reduced Incident Dementia in Older Adults With Type 2 Diabetes

Metformin Use Is Associated With Slowed Cognitive Decline and Reduced Incident Dementia in Older Adults With Type 2 Diabetes: The Sydney Memory and Ageing Study Katherine Samaras, Steve Makkar, John D. Crawford, Nicole A. Kochan, Wei Wen, Brian Draper, Julian … Continue reading

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Is Particulate Matter of Air Pollution a Vector of Covid-19 Pandemic?

Summary
The COVID-19 pandemic is a severe respiratory disease caused by the emergence of a new coronavirus, SARS-CoV-2, that very quickly spread in the human population. Fine particulate matter (PM) generated from combustion engines have been described as toxic to human health. Recent events stressed that high concentrations of PM of air pollution might favor the spread of SARS-CoV-2. Autumn approaches, air pollution will be accentuated because of weather condition. The risk of a second outbreak of Covid-19 pandemic is highly probable. Elucidating the role of PM of air pollution in the spread of the virus is thus urgent and crucial. Continue reading

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Evidence-based prevention of Alzheimer’s disease: systematic review

Results A total of 44 676 reports were identified, and 243 OPSs and 153 RCTs were eligible for analysis after exclusion based on pre-decided criteria, from which 104 modifiable factors and 11 interventions were included in the meta-analyses. Twenty-one suggestions are proposed based on the consolidated evidence, with Class I suggestions targeting 19 factors: 10 with Level A strong evidence (education, cognitive activity, high body mass index in latelife, hyperhomocysteinaemia, depression, stress, diabetes, head trauma, hypertension in midlife and orthostatic hypotension) and 9 with Level B weaker evidence (obesity in midlife, weight loss in late life, physical exercise, smoking, sleep, cerebrovascular disease, frailty, atrial fibrillation and vitamin C). In contrast, two interventions are not recommended: oestrogen replacement therapy (Level A2) and acetylcholinesterase inhibitors (Level B). Continue reading

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