Tag Archives: Mortality

Dementia and Alzheimers’ Disease – How Can It Be Treated?

Dementia and Alzheimers’ Disease – How Can It Be Treated?

The Latin word “De-mentia”, literally means, the removal of a person from their own mind. It stands for a significant decrease in brain function, including memory, goal-directed thinking, orientation in space and time, and language ability.

Most dementias are progressive. They cannot be cured and will gradually cause more severe problems for the patient, and for the patient’s caretakers. As the population ages, Alzheimer’s disease is on its way to becoming the third most common fatal disease.

Prescription medications on the market starting in the 1990s to treat dementia have been a disappointment to patients and doctors alike.

The frustration caused by this situation prompted me to make the development of an anti-dementia treatment protocol a major focus of my clinical work.

As always, we start with a thorough neuropsychiatric assessment, looking for potentially reversible causes of cognitive decline such as a thyroid condition, vitamin deficiency, a sleep disorder, elevated blood sugar and diabetes. Importantly, untreated depression and chronic high stress and anxiety levels are associated with a higher risk for dementia. Most of the time, psychotherapy is a far better alternative to the all-too-common multiple prescription drugs.

The protocol uses a number of carefully evaluated novel interventions and components based on sound neuroscientific principles, sourced from both functional medicine and traditional medical systems, such as Ayurvedic and traditional Chinese medicine.

The protocol stabilizes many of my patients, and improves their functioning and quality of life. It has shown promising results not only for dementia, but also for traumatic brain injury. Continue reading

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Metformin use after Cervical Cancer Diagnosis among Older Women with Diabetes may be Associated with a Significant Decrease in Mortality

Metformin use after Cervical Cancer Diagnosis among Older Women with Diabetes may be Associated with a Significant Decrease in Mortality http://tinyurl.com/jjrnofe Kathy Han1,2,*, Melania Pintilie3, Lorraine L. Lipscombe4,55, Iliana C. Lega4, Michael F. Milosevic1,2, and Anthony W. Fyles1,2 1Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. 2Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada. 3Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. 4Women’s College Research Institute, Women’s College Hospital, Toronto, Ontario, Canada. 5Institute … Continue reading

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Recognizing and preventing epilepsy-related mortality

Recognizing and preventing epilepsy-related mortality http://tinyurl.com/gp8oojy Orrin Devinsky, MD, Tanya Spruill, PhD, David Thurman, MD, PhD and Daniel Friedman, MD, MSc +SHOW AFFILIATIONS | + SHOW FULL DISCLOSURES Correspondence to Dr. Devinsky: od4@nyu.edu Published online before print December 16, 2015doi:http:/​/​dx.​doi.​org/​10.​1212/​WNL.​0000000000002253Neurology February 23, 2016 vol. 86 no. 8 779-786 ABSTRACT Epilepsy is associated with a high rate of premature mortality from direct and indirect effects of seizures, epilepsy, and antiseizure therapies. Sudden unexpected death in epilepsy (SUDEP) is the second leading neurologic cause of total lost potential life-years after stroke, … Continue reading

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Cause of death and predictors of mortality in a community-based cohort of people with epilepsy

Cause of death and predictors of mortality in a community-based cohort of people with epilepsy http://tinyurl.com/hdbgazx Mark R. Keezer, MDCM, MSc, FRCP(C), Gail S. Bell, MB, ChB, MD, Aidan Neligan, PhD, MRCP, Jan Novy, MD, PhD and Josemir W. Sander, MD, PhD, FRCP +SHOW AFFILIATIONS| + SHOW FULL DISCLOSURES Correspondence to Dr. Sander: l.sander@ucl.ac.uk Published online before print January 15, 2016doi:http:/​/​dx.​doi.​org/​10.​1212/​WNL.​0000000000002390Neurology February 23, 2016 vol. 86 no. 8 704-712 ABSTRACT Objective: The risk of premature mortality is increased in people with epilepsy. The reasons for this and how it … Continue reading

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Increasing Benzodiazepine Prescriptions and Overdose Mortality in the United States, 1996–2013

Increasing Benzodiazepine Prescriptions and Overdose Mortality in the United States, 1996–2013 http://tinyurl.com/jqlst3n Marcus A. Bachhuber, MD, MSHP, Sean Hennessy, PharmD, PhD, Chinazo O. Cunningham, MD, MS, and Joanna L. Starrels, MD, MS Marcus A. Bachhuber, Chinazo O. Cunningham, and Joanna L. Starrels are with Division of General Internal Medicine, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY. Sean Hennessy is with Center for Clinical Epidemiology and Biostatistics and Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, Philadelphia. … Continue reading

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Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports

Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports http://tinyurl.com/hmgdrmx Tarang Sharma, PhD student1 2, Louise Schow Guski, medical student1 2, Nanna Freund, medical student1 2, Peter C Gøtzsche, professor1 2 Author affiliations Correspondence to: T Sharma Nordic Cochrane Centre, Rigshospitalet, Blegdamsvej 9, Department 7811, 2100 Ø Copenhagen, Denmark ts@cochrane.dk Accepted 3 December 2015 Abstract Objective To study serious harms associated with selective serotonin and serotonin-norepinephrine reuptake inhibitors. Design Systematic review and meta-analysis. Main outcome measures Mortality and suicidality. Secondary outcomes were … Continue reading

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Mortality Trends Among Working-Age Whites: The Untold Story

Mortality Trends Among Working-Age Whites: The Untold Story http://tinyurl.com/grfw6rq Abstract Recent research has called attention to an unexpected rise in death rates among middle-aged, white Americans between 1999 and 2014. The full extent of the phenomenon may be underappreciated, however. If one assumes, based on historical trends, that mortality rates should have declined by 1.8 percent per year, then whites in 2014 had higher-than-expected mortality rates from age 19 to age 65. Furthermore, while increased substance abuse and suicides explain the elevated mortality rates for … Continue reading

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