Tag Archives: Traumatic Brain Injury

Alzheimer’s Disease – what is it and how can it be treated?

Alzheimer’s Disease – what is it and how can it be treated? Continue reading

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Dementia and Alzheimers’ Disease – How Can It Be Treated?

Dementia and Alzheimers’ Disease – How Can It Be Treated?

The Latin word “De-mentia”, literally means, the removal of a person from their own mind. It stands for a significant decrease in brain function, including memory, goal-directed thinking, orientation in space and time, and language ability.

Most dementias are progressive. They cannot be cured and will gradually cause more severe problems for the patient, and for the patient’s caretakers. As the population ages, Alzheimer’s disease is on its way to becoming the third most common fatal disease.

Prescription medications on the market starting in the 1990s to treat dementia have been a disappointment to patients and doctors alike.

The frustration caused by this situation prompted me to make the development of an anti-dementia treatment protocol a major focus of my clinical work.

As always, we start with a thorough neuropsychiatric assessment, looking for potentially reversible causes of cognitive decline such as a thyroid condition, vitamin deficiency, a sleep disorder, elevated blood sugar and diabetes. Importantly, untreated depression and chronic high stress and anxiety levels are associated with a higher risk for dementia. Most of the time, psychotherapy is a far better alternative to the all-too-common multiple prescription drugs.

The protocol uses a number of carefully evaluated novel interventions and components based on sound neuroscientific principles, sourced from both functional medicine and traditional medical systems, such as Ayurvedic and traditional Chinese medicine.

The protocol stabilizes many of my patients, and improves their functioning and quality of life. It has shown promising results not only for dementia, but also for traumatic brain injury. Continue reading

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A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer’s disease

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer’s disease http://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-28 Ingrid Van der Auwera, Stefaan Wera, Fred Van Leuven and Samuel T HendersonEmail author Nutrition & Metabolism20052:28 DOI: 10.1186/1743-7075-2-28 ©  Van der Auwera et al; licensee BioMed Central Ltd. 2005 Received: 09 August 2005 Accepted: 17 October 2005 Published: 17 October 2005 Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that primarily strikes the elderly. Studies in both humans and animal models have linked the consumption of cholesterol and saturated fats with amyloid-β (Aβ) deposition and development of AD. Yet, these studies did … Continue reading

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Neuroprotective and disease-modifying effects of the ketogenic diet

Neuroprotective and disease-modifying effects of the ketogenic diet Behav Pharmacol. Author manuscript; available in PMC 2008 May 5. Published in final edited form as: Behav Pharmacol. 2006 Sep; 17(5-6): 431–439. Reading it again.. Well worth it. Abstract The ketogenic diet has been in clinical use for over 80 years, primarily for the symptomatic treatment of epilepsy. A recent clinical study has raised the possibility that exposure to the ketogenic diet may confer long-lasting therapeutic benefits for patients with epilepsy. Moreover, there is evidence from uncontrolled … Continue reading

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Stress resilience and subsequent risk of type 2 diabetes in 1.5 million young men

  http://link.springer.com/article/10.1007/s00125-015-3846-7 Stress resilience and subsequent risk of type 2 diabetes in 1.5 million young men Casey Crump  , Jan Sundquist , Marilyn A. Winkleby , Kristina Sundquist $39.95 / €34.95 / £29.95 * * Final gross prices may vary according to local VAT. Get Access Abstract Aims/hypothesis Psychosocial stress in adulthood is associated with a higher risk of type 2 diabetes, possibly mediated by behavioural and physiological factors. However, it is unknown whether low stress resilience earlier in life is related to subsequent development of type 2 diabetes. We examined whether low … Continue reading

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Neuroprotective and disease-modifying effects of the ketogenic diet

Behav Pharmacol. 2006 Sep; 17(5-6): 431–439.  PMCID: PMC2367001 NIHMSID: NIHMS42857 Neuroprotective and disease-modifying effects of the ketogenic diet Maciej Gasior,a Michael A. Rogawski,a and  Adam L. Hartmana,b Author information ► Copyright and License information ► The publisher’s final edited version of this article is available at Behav Pharmacol See other articles in PMC that cite the published article. Go to: Abstract The ketogenic diet has been in clinical use for over 80 years, primarily for the symptomatic treatment of epilepsy. A recent clinical study has raised the possibility that exposure to the ketogenic diet may confer … Continue reading

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DIET, KETONES AND TRAUMATIC BRAIN INJURY

DIET, KETONES AND TRAUMATIC BRAIN INJURY Technical but of great interest. We are successfully using the ketogenic diet alongside other multiple anti-inflammatory approaches. If you want to try this treatment modality for TBI or cognitive impairment (dementia), please contact the office. Published in final edited form as: Epilepsia. 2008 November ; 49(Suppl 8): 111–113. DIET, KETONES AND NEUROTRAUMA Mayumi Prins, Ph.D. UCLA David Geffen School of Medicine, Department of Neurosurgery SUMMARY The annual incidence of traumatic brain injury far exceeds the rates of any other … Continue reading

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Autoimmune disease, inflammation and the brain

Went to a fabulous lecture by  Dr. Souhel Najjar on autoimmune encephalitis this morning. As a reminder, bad relationships (including with one’s self-image etc.) can also cause/contribute to inflammatory burden. Below is a well-informed and written piece on Anti-NMDA-receptor encephalitis (one of many), courtesy of Wikipedia. Last edited 11 days ago by an anonymous user Anti-NMDA receptor encephalitis Watch this page Anti-NMDA (N-methyl D-aspartate) receptor antibody encephalitis, also termed NMDA receptor antibody encephalitis, is an acute form of encephalitis which is potentially lethal but has high probability for … Continue reading

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Flatworms Recall Familiar Environs, Even after Losing Their Heads: Scientific American

Flatworms Recall Familiar Environs, Even after Losing Their Heads: Scientific American. Highly recommended reading. As it turns out, one does not have to go all the way down the evolutionary ladder to be reminded that even brain-impaired or brain-damaged individuals (whether through TBI, dementia, various levels of unconsciousness, or simply sleep) have not only memories, but continue to experience emotions, good and bad. As an illustration that the brain is made of many different levels and parts, here is a recent paper by Feinstein et … Continue reading

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Piperine and curcumin exhibit synergism in attenuating D-galactose induced senescence in rats.

Piperine and curcumin exhibit synergism in attenuating D-galactose induced senescence in rats. Banji D, Banji OJ, Dasaroju S, Annamalai AR. Source Department of Pharmacology, Nalanda College of Pharmacy, Charlapally, Nalgonda 508001, A.P., India. davidbanji@gmail.com Abstract Aging is associated with progressive decline in mental abilities and functional capacities. Postmitotic tissues are most vulnerable to alteration due to oxidative damage leading to behavioral and biochemical changes. We hypothesized that the anatomical and functional facets of the brain could be protected with powerful antioxidants such as piperine and … Continue reading

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Identification of candidate IgG biomarkers for Alzheimer’s disease via combinatorial library screening.

This is important news. Cell. 2011 Jan 7;144(1):132-42. doi: 10.1016/j.cell.2010.11.054. Identification of candidate IgG biomarkers for Alzheimer’s disease via combinatorial library screening. Reddy MM, Wilson R, Wilson J, Connell S, Gocke A, Hynan L, German D, Kodadek T. Source Opko Health Laboratories, Jupiter, FL 33458, USA. Abstract The adaptive immune system is thought to be a rich source of protein biomarkers, but diagnostically useful antibodies remain unknown for a large number of diseases. This is, in part, because the antigens that trigger an immune response … Continue reading

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Calorie restriction: what recent results suggest for the future of ageing research.

Eur J Clin Invest. 2010 May;40(5):440-50. doi: 10.1111/j.1365-2362.2010.02276.x. Calorie restriction: what recent results suggest for the future of ageing research. Smith DL Jr, Nagy TR, Allison DB. Source Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA. dsmithjr@uab.edu Abstract BACKGROUND: Calorie Restriction (CR) research has expanded rapidly over the past few decades and CR remains the most highly reproducible, environmental intervention to improve health and extend lifespan in animal studies. Although many model organisms have consistently demonstrated positive responses to CR, … Continue reading

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