Association between sleep disorders and injury: a nationwide population-based retrospective cohort study
Chia-Ling Lin1,2, Chi-Hsiang Chung3, Yu-Hsia Tsai1,4, Wu-Chien Chien5,6
Author Affiliations
1School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan 2Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan 3Taiwanese Injury Prevention and Safety Promotion Association, Taipei, Taiwan 4Department of Nursing, College of Medicine, Chang Gung University, Taoyuan, Taiwan 5Department of Medical Research, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan 6School of Public Health, National Defense Medical Center, Taipei, TaiwanCorrespondence to
Professor Wu-Chien Chien, Address: No. 325, Sec. 2, Cheng-Kung Rd., Neihu Dist., Taipei City 114, Taiwan; chienwu@ndmctsgh.edu.tw
Received 10 September 2015
Revised 5 January 2016
Accepted 22 January 2016
Published Online First 18 February 2016
Abstract
Background The evidence is insufficient for the association between the exposure of sleep disorders and the risk of injury. The aim of this study was to examine the association between patients with sleep disorders and the risk of injury.
Methods This was a population-based retrospective cohort study using Taiwan National Health Insurance Research Database from 2005 to 2010. A total of 15 109 patients with sleep disorders were identified as the study cohort. The non-sleep disorders control cohort comprised 29 955 age- and sex-matched patients. We conducted a Cox proportional hazard regression analysis to estimate the effects of sleep disorders on the risk of injury.
Results The overall incidence of injury was 77.03 per 1000 person-years for patients with sleep disorders, which was significantly higher than that of the control cohort (60.63 per 1000 person-years). Overall, patients with sleep disorders had a higher risk of injury compared with control cohort (adjusted HR=1.27, 95% CI 1.26 to 1.28). Comparing to the control cohort, patients with insomnia had a 12% higher risk for injury (adjusted HR, 1.12 (95% CI 1.01 to 1.41)).
Conclusions Comparing to patients with non-sleep disorders, patients with sleep disorders had a higher risk of injury and the risk was particularly pronounced in those who had insomnia.
