The Brain Injury Guidelines (BIG)

The Brain Injury Guidelines (BIG) classify traumatic brain injuries into three categories – BIG 1, BIG 2, and BIG 3 – based on the severity of the injury and imaging findings. Here are the key differences between these categories:

## BIG 1

– Smallest/mildest injuries
– Intracranial hemorrhage ≤ 4 mm in size
– No skull fractures
– No anticoagulation/antiplatelet therapy
– No intraventricular hemorrhage (IVH)
– Managed with 6-hour observation in the emergency department
– No planned neurosurgery consultation or repeat head CT

## BIG 2

– Moderate injuries
– Intracranial hemorrhage 4-7 mm in size
– May have non-displaced skull fractures
– No anticoagulation/antiplatelet therapy
– No IVH
– Admitted to the hospital
– No planned neurosurgery consultation or repeat head CT

## BIG 3

– Largest/most severe injuries
– Intracranial hemorrhage ≥ 8 mm in size
– May have displaced skull fractures
– May be on anticoagulation/antiplatelet therapy
– May have IVH
– Admitted to the hospital
– Mandatory neurosurgical consultation
– Repeat head CT at 6 hours
– Frequent neurological checks

The key differences lie in the size of the intracranial hemorrhage, presence of skull fractures, use of anticoagulants, and the management approach. BIG 1 patients can potentially be discharged after brief observation, BIG 2 patients require hospital admission but not necessarily neurosurgical consultation, while BIG 3 patients need the most intensive management with neurosurgical involvement and repeat imaging[1].

Citations:
[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC7264829/
[2] https://www.law-wv.com/blog/2021/february/the-3-levels-of-brain-injuries/

Maurice Preter, MD

About Maurice Preter MD

Maurice Preter, MD is a European and U.S. educated psychiatrist, psychotherapist, psychopharmacologist, neurologist, and medical-legal expert in private practice in Manhattan. He is also the principal of Fifth Avenue Concierge Medicine, PLLC, a medical concierge service and health advisory for select individuals and families.
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