Vitamin-D and COVID-19: do deficient risk a poorer outcome?

Source: DOI:https://doi.org/10.1016/S2213-8587(20)30183-2

“Despite difficulties in comparing data across nations, mortality from COVID-19 is clearly higher in some countries than in others. Many factors could have a role in this disparity, including differences in proportion of elderly people in a population, general health, accessibility and quality of healthcare, and socioeconomic status. One mostly overlooked factor that could influence outcome of COVID-19 is the relative vitamin D status of populations.” […]
 
 
Posted in Aging, dietary, epigenetics, Fifth Avenue Concierge Medicine, Forensic Neuropsychiatry, Health, News, Psychiatry/Neurology | Tagged , , |

detectstudy.org

Very important. Your smartwatch heart rate signal as an early warning sign of illness. https://detectstudy.org/ for more. https://www.thelancet.com/journals/landig/article/PIIS2589-7500(19)30222-5/fulltext for research background.

Posted in News | Tagged , |

What is Telepsychiatry?

Telemedicine is the process of providing health care from a distance through technology, often using videoconferencing. Telepsychiatry, a subset of telemedicine, can involve providing a range of services including psychiatric evaluations, therapy (individual therapy, group therapy, family therapy), patient education and medication management.

Telepsychiatry can involve direct interaction between a psychiatrist and the patient. It also encompasses psychiatrists supporting primary care providers with mental health care consultation and expertise. Mental health care can be delivered in a live, interactive communication. It can also involve recording medical information (images, videos, etc.) and sending this to a distant site for later review.

Benefits

Video-based telepsychiatry helps meet patients’ needs for convenient, affordable and readily-accessible mental health services. It can benefit patients in a number of ways, such as:

  • Improve access to mental health specialty care that might not otherwise be available (e.g., in rural areas)
  • Bring care to the patient’s location
  • Help integrate behavioral health care and primary care, leading to better outcomes
  • Reduce the need for trips to the emergency room
  • Reduce delays in care
  • Improve continuity of care and follow-up
  • Reduce the need for time off work, childcare services, etc. to access appointments far away
  • Reduce potential transportation barriers, such as lack of transportation or the need for long drives
  • Reduce the barrier of stigma

While some people may be reluctant or feel awkward talking to person in a screen, experience shows most people are comfortable with it. Some people may be more relaxed and willing to open up from the comfort of their home or a convenient local facility. Also, this will likely be less of a problem as people become more familiar and comfortable with video communication in everyday life.

Telepsychiatry allows psychiatrists to treat more patients in distant locations. Psychiatrists and other clinicians need to be licensed in the state(s) where the patient they are working with is located. State licensing boards and legislatures view the location of the patient as the place where “the practice of medicine” occurs.

Although telepsychiatry has the disadvantage of the patient and psychiatrist not being in the same room, it can create enhanced feelings of safety, security and privacy for many patients.

Evidence for Effectiveness

There is substantial evidence of the effectiveness of telepsychiatry and research has found satisfaction to be high among patients, psychiatrists and other professionals. Telepsychiatry is equivalent to in-person care in diagnostic accuracy, treatment effectiveness, quality of care and patient satisfaction. Patient privacy and confidentiality are equivalent to in-person care.

Research has also found that overall experiences among all age groups have been good. There is evidence for children, adolescents and adults regarding assessment and treatment (medication and therapy). There are even people for which telemedicine may be preferable to in-person care, for example people with autism or severe anxiety disorders and patients with physical limitations may find the remote treatment particularly useful.

Telepsychiatry has been found especially effective with respect to the treatment of PTSD, depression, and ADHD. See more on the evidence base for telepsychiatry.

Used in a Variety of Settings

Telepsychiatry is used in a variety of different settings, including private practice, outpatient clinics, hospitals, correctional facilities, schools, nursing homes, and military treatment facilities.

Patients can schedule appointments individually with a psychiatrist or therapist for a live video appointment. This can be with a regular provider if they offer the service or through one of a number of companies offering access to mental health clinicians for video appointments. Patients should plan ahead and prepare the just as for an in-person appointment. Have any relevant records and information, including prescriptions, and have a list of questions to address.

Telepsychiatry is helping bring more timely psychiatric care to emergency rooms. An estimated one in eight emergency room visits involves a mental health and/or substance use condition, according to the Agency for Healthcare Research and Quality. Many emergency rooms are not equipped to handle people with serious mental health issues and do not have psychiatrists or other mental health clinicians on staff to assess and treat mental health problems. A 2016 poll of emergency room physicians found only 17 percent reported having a psychiatrist on call to respond to psychiatric emergencies.

Telepsychiatry is being used in nursing homes to provide both ongoing psychiatric evaluation and care and emergency crisis intervention when it may be difficult to find local psychiatrist to assist. Many states use telepsychiatry in corrections facilities where inmates frequently require ongoing mental health care.

Source:
https://www.psychiatry.org/patients-families/what-is-telepsychiatry

Posted in Events, Fifth Avenue Concierge Medicine, new treatments, Psychiatry/Neurology | Tagged , , |

Guidance for 2019 Corona Virus Disease: Prevention, Control, Diagnosis and Management

Professor Wang XP, Chairman of the Department of Neurology at Shanghai First People’s Hospital, Jiao-Tong University, Shanghai, China, was so kind and forwarded the following interesting text based on China’s experience with Covid-19. Like everything else on this site, it’s not medical advice. One day, ones hopes, it will simply be a historic document. https://mp.weixin.qq.com/s/nOAmosQ4YqkXHKdJbBE9GA

Posted in China, Complementary - Alternative Medicine, News | Tagged , , |

Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression

Abstract

Recently, increasing evidence has suggested the association between gut dysbiosis and Alzheimer’s disease (AD) progression, yet the role of gut microbiota in AD pathogenesis remains obscure. Herein, we provide a potential mechanistic link between gut microbiota dysbiosis and neuroinflammation in AD progression. Using AD mouse models, we discovered that, during AD progression, the alteration of gut microbiota composition leads to the peripheral accumulation of phenylalanine and isoleucine, which stimulates the differentiation and proliferation of pro-inflammatory T helper 1 (Th1) cells. The brain-infiltrated peripheral Th1 immune cells are associated with the M1 microglia activation, contributing to AD-associated neuroinflammation. Importantly, the elevation of phenylalanine and isoleucine concentrations and the increase of Th1 cell frequency in the blood were also observed in two small independent cohorts of patients with mild cognitive impairment (MCI) due to AD. Furthermore, GV-971, a sodium oligomannate that has demonstrated solid and consistent cognition improvement in a phase 3 clinical trial in China, suppresses gut dysbiosis and the associated phenylalanine/isoleucine accumulation, harnesses neuroinflammation and reverses the cognition impairment. Together, our findings highlight the role of gut dysbiosis-promoted neuroinflammation in AD progression and suggest a novel strategy for AD therapy by remodelling the gut microbiota.

 

https://www.nature.com/articles/s41422-019-0216-x

Posted in China, Complementary - Alternative Medicine, development, dietary, epigenetics | Tagged , , , , , |