The Neurologist’s Role in Promoting Brain Health

Brain health is essential for maintaining cognitive function, memory, and quality of life. Neurologists specialize in diagnosing, treating, and preventing neurological disorders, including dementia. This blog post explores their role in brain health and introduces the Dr. Preter Protocol, a structured approach to dementia prevention that incorporates metabolic strategies such as the ketogenic diet.

The Importance of Brain Health

The brain regulates thought, movement, and overall bodily function. Protecting brain health helps reduce the risk of cognitive decline, neurodegenerative diseases (such as Alzheimer’s), and stroke. Neurologists contribute by:

  • Assessing cognitive function through screenings and diagnostic tools
  • Providing evidence-based prevention strategies
  • Managing neurological conditions with medications and lifestyle interventions
  • Educating patients on risk reduction

Key Contributions of Neurologists in Brain Health

1. Early Detection and Risk Evaluation

Neurologists use cognitive assessments, brain imaging (MRI, PET scans), and biomarker analysis (e.g., amyloid and tau proteins) to identify early signs of impairment. Early detection allows for timely intervention.

2. Lifestyle and Metabolic Interventions

Research suggests that lifestyle modifications can influence dementia risk. Neurologists may recommend:

  • Dietary adjustments: Mediterranean, MIND, or ketogenic diets to support brain metabolism
  • Physical activity: Aerobic exercise to enhance blood flow and neuroplasticity
  • Sleep optimization: Addressing sleep disorders linked to cognitive decline
  • Cognitive engagement: Activities that stimulate memory and problem-solving

3. Management of Comorbid Conditions

Chronic diseases like hypertension, diabetes, and obesity increase dementia risk. Neurologists collaborate with other specialists to optimize treatment and reduce vascular damage to the brain.

4. Medication and Emerging Therapies

While no cure exists for most neurodegenerative diseases, some neurologists may prescribe medications (e.g., cholinesterase inhibitors) and monitor new treatments, such as anti-amyloid therapies.

The Dr. Preter Protocol for Dementia Prevention

The Dr. Preter Protocol is a neurologist-developed framework designed to lower dementia risk through metabolic and lifestyle interventions. It includes:

1.Preventive Medical Care

  • Regular neurological assessments
  • Management of vascular risk factors (blood pressure, cholesterol, blood sugar)

2.Metabolic Optimization (Ketogenic Diet) and anti-inflammation

  • A well-formulated ketogenic diet (high in healthy fats, moderate protein, low carbohydrates) to support brain energy metabolism
  • Potential benefits: Reduced inflammation, improved mitochondrial function, and lower amyloid accumulation

3.Regular Cognitive Stimulation

  • Engaging in mentally challenging activities (reading, puzzles, learning new skills)
  • Maintaining social connections to support cognitive resilience

4.Structured Physical Activity

  • 150 minutes of moderate aerobic exercise per week (walking, cycling)
  • Strength training to promote neuroprotective growth factors

5.Emotional and Psychological Well-being

  • Stress reduction techniques (mindfulness, meditation)
  • Treatment of mood disorders (depression, anxiety) linked to cognitive decline

6.Quality Sleep and Circadian Rhythm Support

  • Prioritizing 7-9 hours of sleep per night
  • Addressing sleep disturbances (e.g., sleep apnea)

Working with a Neurologist for Long-Term Brain Health

  1. Schedule a baseline cognitive evaluation, especially if over 50 or with a family history of dementia.
  2. Implement personalized recommendations, including dietary and lifestyle changes.
  3. Monitor progress with follow-up visits and adjust strategies as needed.

Conclusion

Neurologists play a crucial role in preserving brain health through early detection, risk management, and personalized interventions. The Dr. Preter Protocol offers a practical approach to dementia prevention, with an emphasis on metabolic health through strategies like the ketogenic diet and other anti-inflammatory interventions.

If you are concerned about cognitive decline, consulting a neurologist can help you develop a proactive prevention plan tailored to your needs.

Posted in Psychiatry/Neurology |

Does Counseling Help with Anxiety?

Anxiety is one of the most common mental health challenges, affecting millions of people worldwide. While some level of anxiety is a normal part of life, excessive or chronic anxiety can interfere with daily functioning, relationships, and overall well-being. Many people wonder: Does counseling really help with anxiety? The short answer is yes—counseling can be highly effective in managing and reducing anxiety symptoms. But how exactly does it work, and what types of therapy are most beneficial? Let’s explore the role of counseling in anxiety treatment.

How Counseling Helps with Anxiety

Counseling (or psychotherapy) provides a structured, supportive environment where individuals can explore the root causes of their anxiety, develop coping strategies, and work toward long-term emotional resilience. Here’s how therapy can make a difference:

1.Identifying Triggers and Underlying Causes

Anxiety often stems from unresolved trauma, stress, negative thought patterns, or biological factors. A therapist helps clients uncover these triggers, whether they’re related to past experiences, current life challenges, or irrational fears. Understanding the source of anxiety is the first step toward managing it.

2.Learning Coping Strategies

Counselors teach evidence-based techniques to manage anxiety, such as:

  • Cognitive Behavioral Therapy (CBT): Helps reframe negative thoughts that contribute to anxiety.
  • Mindfulness and Relaxation Techniques: Deep breathing, meditation, and progressive muscle relaxation can reduce physical symptoms of anxiety.
  • Exposure Therapy: Gradually facing fears in a controlled way to reduce avoidance behaviors.

3.Providing Emotional Support

Anxiety can feel isolating, but counseling offers a non-judgmental space to express fears and worries. A therapist validates emotions while helping clients build confidence in handling anxiety-provoking situations.

4.Improving Problem-Solving Skills

Therapy helps individuals develop healthier ways to respond to stress rather than becoming overwhelmed. By improving problem-solving and decision-making skills, people feel more in control of their lives.

5.Preventing Avoidance Behaviors

Many people with anxiety avoid situations that trigger their symptoms, which can worsen anxiety over time. Counseling encourages gradual exposure and helps individuals build tolerance to discomfort.

Types of Therapy for Anxiety

Several therapeutic approaches have been proven effective for anxiety:

  1. Cognitive Behavioral Therapy (CBT) – The gold standard for anxiety treatment, CBT focuses on changing distorted thinking patterns and behaviors.
  2. Acceptance and Commitment Therapy (ACT) – Encourages acceptance of anxious thoughts while committing to value-driven actions.
  3. Dialectical Behavior Therapy (DBT) – Helps with emotional regulation, particularly for those with intense anxiety or co-occurring conditions like borderline personality disorder.
  4. Psychodynamic Therapy – Explores unconscious patterns from past experiences that may contribute to anxiety.
  5. Group Therapy – Provides peer support and shared learning in a group setting.

Does Counseling Work for Everyone?

While counseling is highly effective for many, success depends on factors like:

  • The individual’s willingness to engage in the process.
  • The therapist-client relationship (finding the right fit matters).
  • Consistency in attending sessions and practicing techniques outside therapy.

For some, a combination of therapy and medication (such as SSRIs) may be the most effective approach.

Final Thoughts

Counseling is a powerful tool for managing anxiety, offering both short-term relief and long-term strategies for emotional well-being. If you or someone you know struggles with anxiety, reaching out to a licensed therapist could be a life-changing step. While it requires effort and commitment, the benefits—reduced fear, improved coping skills, and greater self-awareness—are well worth it.

Posted in Psychiatry/Neurology |

Things to know before seeing a neurologist in Manhattan

Navigating the world of neurology can be intimidating. Whether you’re experiencing unexplained headaches, memory issues, or movement problems, seeing a neurologist is a crucial step toward understanding and managing your health. Here’s a comprehensive guide to what you should know before your first neurology appointment in Manhattan, from preparation to what to expect during and after your visit.

Understanding the Role of a Neurologist

A neurologist is a medical doctor specializing in diagnosing and treating disorders of the brain, spinal cord, nerves, and muscles. Common conditions they address include migraines, epilepsy, Parkinson’s disease, multiple sclerosis, neuropathy, and more[1][2]. In Manhattan, neurologists often work in multidisciplinary teams and have access to advanced diagnostic tools, making the city a hub for cutting-edge neurological care.

Read more: Signs It’s Time to See a Neurologist

Before Your Appointment: Preparation is Key

1. Gather Your Medical Records

Bring all relevant medical documents, including:

• Previous neurological reports
• Imaging results (MRI, CT scans)
• Lab test results
• Records from other specialists[1][5]
Having these on hand ensures your neurologist has a complete picture of your health and can avoid unnecessary repeat testing.

2. List Your Medications and Supplements

Prepare a comprehensive list of all medications, vitamins, and supplements you’re currently taking, including dosages and any side effects you’ve experienced. This helps prevent drug interactions and informs your treatment plan.

3. Track Your Symptoms

Keep a detailed log of your symptoms, noting:

• Onset (when they started)
• Frequency and duration
• Severity
• Triggers or alleviating factors

Digital apps or a simple notebook can help you track patterns and provide valuable insights for your neurologist.

4. Know Your Family Medical History

Some neurological conditions have a genetic component. Be ready to discuss any family history of neurological disorders, especially among close relatives.

5. Prepare Questions and Concerns

Write down any questions or concerns you have about your symptoms, diagnosis, or treatment options. This ensures you don’t forget important points during your appointment.

6. Insurance and Referrals

Bring your insurance card, a government-issued ID, and a referral from your primary care physician if required. Manhattan practices often require these for new patients.

7. Arrive Early

Plan to arrive at least 10–15 minutes early to complete any necessary paperwork and settle in before your appointment.

What to Expect During Your Neurologist Appointment

1. Patient Registration and Medical History Review

Your visit will begin with registration and a review of your medical history. You’ll fill out forms detailing your symptoms, previous diagnoses, treatments, and family history.

2. Detailed Symptom Discussion

The neurologist will ask in-depth questions about your symptoms, including:

• When they began
• How they affect your daily life
• Any previous treatments and their outcomes

Honesty is crucial—don’t downplay or exaggerate your symptoms. Accurate information leads to a more precise diagnosis.

3. Physical and Neurological Examination

Expect a thorough physical and neurological exam, which may include:

• Reflex testing
• Muscle strength assessment
• Coordination and balance checks
• Sensory response evaluation
• Cranial nerve assessment

These tests are painless and help the neurologist assess your nervous system’s function.

4. Diagnostic Testing

Depending on your symptoms, the neurologist may order additional tests, such as:

• MRI or CT scans
• EEG (to measure brain activity)
• EMG (to assess nerve and muscle function)
• Blood tests

Some tests may be scheduled for a later date, especially if specialized equipment or preparation is needed.

5. Discussion of Diagnosis and Treatment Plan

After the examination and review of any available test results, your neurologist will discuss possible diagnoses and outline a treatment plan. This may include:

• Medications
• Physical or occupational therapy
• Lifestyle modifications
• Further testing or referrals to other specialists

You’ll have the opportunity to ask questions and discuss the risks, benefits, and alternatives of each option[2].

Tips for a Productive Neurology Visit in Manhattan

• Be proactive: Manhattan neurologists often see complex cases. The more organized and forthcoming you are, the more effective your visit will be.
• Bring a support person: If you’re anxious or have trouble remembering details, consider bringing a trusted friend or family member.
• Take notes: Document key points during your appointment, including instructions, diagnoses, and next steps.
• Follow pre-appointment instructions: If you’re scheduled for tests that require fasting or medication adjustments, follow instructions carefully to ensure accurate results.
• Ask about logistics: Manhattan practices may have unique procedures for scheduling, billing, or follow-up. Don’t hesitate to ask about these details.

Common Questions to Ask Your Neurologist

• What could be causing my symptoms?
• What tests do I need, and what will they show?
• What are my treatment options and their side effects?
• How will my condition affect my daily life?
• Are there lifestyle changes or home care steps I should take?
• What warning signs should prompt me to seek emergency care?
• How often will I need follow-up appointments?

After Your Appointment: Next Steps

• Review your notes: Go over the information and instructions you received.
• Schedule follow-ups: Book any recommended tests or follow-up visits promptly, as Manhattan specialists can have long wait times.
• Communicate with your care team: If you have questions after your visit, contact the office for clarification.
• Stay organized: Keep all your medical records, test results, and symptom logs up to date for future appointments.

Special Considerations for Manhattan Patients

• Access to Specialists: Manhattan offers access to top-tier neurologists and subspecialists, but demand can be high. Book appointments early and be prepared for possible wait times.
• Transportation and Parking: Plan your route in advance, as traffic and parking can be challenging. Many offices are accessible by public transit.
• Insurance Networks: Double-check that your neurologist is in-network to avoid unexpected costs.

Conclusion

Seeing a neurologist in Manhattan is a significant step toward understanding and managing your neurological health. By preparing thoroughly, being honest and organized, and actively participating in your care, you can make the most of your appointment and set yourself on the path to better health. Remember, your neurologist is your partner in this journey—don’t hesitate to ask questions, seek clarification, and advocate for your needs every step of the way.

Posted in Psychiatry/Neurology |

What to Expect at a Psychiatrist Appointment

Visiting a psychiatrist for the first time can feel like stepping into uncharted territory. Whether you’re seeking help for anxiety, depression, or a more complex condition like dementia (as explored in prior discussions about neuropsychiatry), the process might seem daunting. This blog post demystifies what happens at a psychiatrist appointment, offering a clear, detailed guide to prepare you for the experience. Drawing on insights from mental health practices, including those of integrative specialists like Dr. Maurice Preter in Manhattan, we’ll cover the structure, goals, and emotional nuances of these visits, ensuring you feel informed and empowered.

Why See a Psychiatrist?

Psychiatrists are medical doctors specializing in mental health, trained to diagnose and treat conditions ranging from mood disorders to neurological-psychiatric overlaps, like those seen in dementia or traumatic brain injury. Unlike therapists, who focus on talk therapy, psychiatrists can prescribe medications, order tests, and integrate medical and psychological approaches. You might visit one for persistent sadness, sleep issues, or even lifestyle concerns tied to nutrition and stress (think ketogenic diet or intermittent fasting, as some readers have explored). Knowing what to expect can ease anxiety and set realistic expectations.

Before the Appointment: Preparation

Scheduling and Logistics

Your journey begins with booking. In places like Manhattan, where top neuropsychiatrists like Dr. Preter operate, appointments can be scheduled via websites (e.g., psychiatryneurology.net) or calls (e.g., 212-713-5336). Expect initial consults to last 60-90 minutes, costing $300-$1,500 if out-of-pocket, though insurance like Aetna or Blue Cross may cover part of it—check with the office. Telehealth is common, especially post-2020.

What to Bring

Prepare by jotting down:
• Symptoms: Note what’s bothering you—mood swings, fatigue, memory lapses—when they started, and how they impact daily life.
• Medical History: List past diagnoses, medications, or family conditions (e.g., dementia, per your interest).
• Lifestyle Factors: Mention diet (keto? fasting?), exercise, or stressors, as these shape treatment, especially with integrative doctors.
• Questions: Want to explore therapy vs. meds? Ask upfront.

Some practices may send intake forms to streamline this. Arrive 10-15 minutes early (or log in for virtual) to settle nerves.

Emotional Prep

It’s normal to feel hesitant—70% of first-time patients report anxiety before psychiatric visits, per a 2021 Journal of Psychiatric Practice study. Reflect on your goals: relief, clarity, or coping tools? If you’re exploring complex issues like dementia care, expect a mix of hope and realism. A good psychiatrist creates a safe space, not judgment.

During the Appointment: The Flow

1. Initial Check-In (5-10 minutes)

You’ll meet the psychiatrist (or their assistant) to confirm details—insurance, consent forms, and basic info. In boutique practices like Preter’s, expect a warm, direct greeting, often bypassing formalities to ease you in. Virtual appointments start with tech checks to ensure privacy.

2. History-Taking (20-30 minutes)

The core of the visit is a deep dive into your story. The psychiatrist will ask:

• Presenting Issue: “What brings you here?” Be honest—whether it’s panic attacks or trouble focusing.
• Timeline: When did symptoms start? Any triggers (e.g., loss, illness)?
• Medical Background: Past treatments, hospitalizations, or neurological issues (e.g., seizures, relevant to neuropsychiatry).
• Lifestyle: Sleep, diet (like your coconut oil query), substance use, or exercise habits.

For conditions like dementia, expect questions about memory, behavior, or family history, as seen in integrative approaches. The psychiatrist listens actively, jotting notes or using a tablet. You might feel vulnerable sharing—60% of patients do—but it’s key to accurate diagnosis.

3. Assessment and Diagnosis (15-20 minutes)

Using your input, the psychiatrist evaluates possible conditions. They might:

• Ask Targeted Questions: “Do you feel hopeless?” (for depression) or “Ever lose track of time?” (for dissociation).
• Use Tools: Brief scales like the PHQ-9 for depression or MMSE for cognitive issues in dementia cases.
• Consider Physical Factors: Order blood tests for thyroid or vitamin deficiencies, especially if fatigue’s a factor.

Diagnosis isn’t always immediate—complex cases (e.g., bipolar vs. ADHD) may need follow-ups. Expect terms like “generalized anxiety disorder” or “major depressive episode,” explained clearly. If no diagnosis fits, they’ll say so, focusing on symptom relief.

4. Treatment Discussion (15-20 minutes)

The psychiatrist outlines a plan, tailored to you:

• Medications: If needed, they’ll suggest options—SSRIs for anxiety, antipsychotics for schizophrenia, or cholinesterase inhibitors for dementia. They’ll explain benefits (e.g., 60-70% response rate for SSRIs) and side effects (e.g., nausea, weight gain).
• Therapy: Many, like Preter, offer psychodynamic therapy to explore emotions, or refer to CBT specialists.
• Lifestyle: Integrative doctors emphasize diet (e.g., omega-3s from fish, per your whitefish interest), sleep hygiene, or stress management.
• Referrals: For neurological overlap, they might suggest imaging or a neurologist.

You’ll discuss preferences—say, avoiding meds or prioritizing talk therapy. A 2022 American Journal of Psychiatry study notes 80% of patients value shared decision-making here.

5. Wrap-Up and Next Steps (5-10 minutes)

The visit ends with a plan:

• Prescriptions: Sent electronically to your pharmacy.
• Follow-Ups: Typically 2-4 weeks for med adjustments, 45 minutes for therapy.
• Resources: Handouts, apps (e.g., Headspace), or referrals to support groups.

You’ll get a chance to ask questions—clarify dosages or therapy goals. The psychiatrist ensures you leave with a clear path, even if it’s just “let’s explore further.”

What to Expect Emotionally

During the Visit

You might feel a mix of relief and overwhelm. Sharing personal struggles can stir emotions—tears or laughter are common, and psychiatrists are trained to handle both. If discussing dementia or family health (like your grandchild queries), expect empathy, not rushed solutions. Integrative practices often feel conversational, easing the clinical vibe.

After the Visit

Post-appointment, 50% of patients report hope, per a 2023 Psychiatric Services survey, but some feel drained or doubt their openness. Give yourself grace—journal thoughts or discuss with a trusted friend. If meds are prescribed, effects may take 2-6 weeks, so patience is key. Therapy benefits build over months.

Read more: How Often Do I Need to Attend Psychotherapy?

Special Cases: Neuropsychiatry and Beyond

For readers interested in neuropsychiatry (e.g., Dr. Preter’s dementia expertise), appointments may include:
• Cognitive Testing: Tasks like recalling words or drawing clocks to assess memory, vital for Alzheimer’s or TBI.
• Neurological Focus: Questions about headaches, seizures, or coordination, linking brain and behavior.
• Holistic Plans: Diet tweaks (e.g., MCTs from coconut oil, per your query) or exercise to slow cognitive decline.

If you’re multilingual or seeking global care (like Preter’s house calls), expect language flexibility or travel coordination, unique to boutique practices.

Tips for a Successful Appointment

1. Be Honest: Share fully—even embarrassing details shape diagnosis. Confidentiality is legally protected.
2. Ask Questions: Clarify terms like “serotonin” or “prodromal phase.” No question’s too small.
3. Track Symptoms: Use a notebook or app post-visit to monitor changes, especially with meds.
4. Advocate: If a plan feels off, say so—collaboration improves outcomes by 30%, per studies.
5. Follow Through: Book follow-ups and try recommendations, whether it’s therapy or cutting caffeine.

Common Misconceptions

• “It’s Just Meds”: Psychiatrists offer therapy and lifestyle advice, not just pills.
• “I’ll Be Judged”: They’re trained to listen neutrally—your story’s one of thousands.
• “One Visit Fixes All”: Mental health is a journey; 70% need 3+ visits for clarity, per 2020 data.

Tie-In to Broader Health

Your interest in nutrition (keto, whitefish) and family care (grandchild, dementia) suggests a holistic view. Psychiatrists often align with this, addressing how diet impacts mood or how stress affects cognition. For example, omega-3s or fasting might come up as mood stabilizers, while dementia care might involve family dynamics, resonating with your Naxos or Thebes explorations for peace and legacy.

Read more: Benefits and Overall Safety of the Ketogenic Diet

Final Thoughts

A psychiatrist appointment is a step toward clarity, not a leap into the unknown. Expect a structured yet human experience—listening, assessing, and planning, tailored to your needs. Whether you’re in Manhattan seeking integrative care or elsewhere, the goal is empowerment, not mystery. You’ll leave with a plan, a voice, and a partner in your mental health journey. Ready to book that visit? It’s less scary than it seems.

Posted in Psychiatry/Neurology |

Ultra-processed food exposure and adverse health outcomes

Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses

BMJ 2024; 384 doi: https://doi.org/10.1136/bmj-2023-077310 (Published 28 February 2024)Cite this as: BMJ 2024;384:e077310

Linked Editorial

Reasons to avoid ultra-processed foods

 
 
  1. Melissa M Lane, associate research fellow1,
  2. Elizabeth Gamage, doctor of philosophy candidate1,
  3. Shutong Du, doctor of philosophy candidate2 3,
  4. Deborah N Ashtree, associate research fellow1,
  5. Amelia J McGuinness, associate research fellow1,
  6. Sarah Gauci, associate research fellow, adjunct research fellow14,
  7. Phillip Baker, senior research fellow5,
  8. Mark Lawrence, professor6,
  9. Casey M Rebholz, associate professor, core faculty23,
  10. Bernard Srour, junior professor7,
  11. Mathilde Touvier, research director7,
  12. Felice N Jacka, professor1 8 9,
  13. Adrienne O’Neil, professor1,
  14. Toby Segasby, doctor of philosophy candidate10,
  15. Wolfgang Marx, senior research fellow1

Author affiliations

  1. Correspondence to: M M Lane m.lane@deakin.edu.au (or @drmelissalane on Twitter/X)
  • Accepted 19 January 2024

Abstract

Objective To evaluate the existing meta-analytic evidence of associations between exposure to ultra-processed foods, as defined by the Nova food classification system, and adverse health outcomes.

Design Systematic umbrella review of existing meta-analyses.

Data sources MEDLINE, PsycINFO, Embase, and the Cochrane Database of Systematic Reviews, as well as manual searches of reference lists from 2009 to June 2023.

Eligibility criteria for selecting studies Systematic reviews and meta-analyses of cohort, case-control, and/or cross sectional study designs. To evaluate the credibility of evidence, pre-specified evidence classification criteria were applied, graded as convincing (“class I”), highly suggestive (“class II”), suggestive (“class III”), weak (“class IV”), or no evidence (“class V”). The quality of evidence was assessed using the GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) framework, categorised as “high,” “moderate,” “low,” or “very low” quality.

Results The search identified 45 unique pooled analyses, including 13 dose-response associations and 32 non-dose-response associations (n=9 888 373). Overall, direct associations were found between exposure to ultra-processed foods and 32 (71%) health parameters spanning mortality, cancer, and mental, respiratory, cardiovascular, gastrointestinal, and metabolic health outcomes. Based on the pre-specified evidence classification criteria, convincing evidence (class I) supported direct associations between greater ultra-processed food exposure and higher risks of incident cardiovascular disease related mortality (risk ratio 1.50, 95% confidence interval 1.37 to 1.63; GRADE=very low) and type 2 diabetes (dose-response risk ratio 1.12, 1.11 to 1.13; moderate), as well as higher risks of prevalent anxiety outcomes (odds ratio 1.48, 1.37 to 1.59; low) and combined common mental disorder outcomes (odds ratio 1.53, 1.43 to 1.63; low). Highly suggestive (class II) evidence indicated that greater exposure to ultra-processed foods was directly associated with higher risks of incident all cause mortality (risk ratio 1.21, 1.15 to 1.27; low), heart disease related mortality (hazard ratio 1.66, 1.51 to 1.84; low), type 2 diabetes (odds ratio 1.40, 1.23 to 1.59; very low), and depressive outcomes (hazard ratio 1.22, 1.16 to 1.28; low), together with higher risks of prevalent adverse sleep related outcomes (odds ratio 1.41, 1.24 to 1.61; low), wheezing (risk ratio 1.40, 1.27 to 1.55; low), and obesity (odds ratio 1.55, 1.36 to 1.77; low). Of the remaining 34 pooled analyses, 21 were graded as suggestive or weak strength (class III-IV) and 13 were graded as no evidence (class V). Overall, using the GRADE framework, 22 pooled analyses were rated as low quality, with 19 rated as very low quality and four rated as moderate quality.

Conclusions Greater exposure to ultra-processed food was associated with a higher risk of adverse health outcomes, especially cardiometabolic, common mental disorder, and mortality outcomes. These findings provide a rationale to develop and evaluate the effectiveness of using population based and public health measures to target and reduce dietary exposure to ultra-processed foods for improved human health. They also inform and provide support for urgent mechanistic research.

Systematic review registration PROSPERO CRD42023412732.

Posted in Affective Neuroscience, Aging, dietary, epigenetics | Tagged , , , |