Finasteride treatment influences neuronal plasticity on a structural level. These changes might contribute to the pathophysiology of depressive episodes observed after finasteride treatment.

Pharmacopsychiatry. 2010 Jul;43(5):174-8. doi: 10.1055/s-0030-1249095. Epub 2010 May 18. Finasteride treatment inhibits adult hippocampal neurogenesis in male mice. Römer B, Pfeiffer N, Lewicka S, Ben-Abdallah N, Vogt MA, Deuschle M, Vollmayr B, Gass P. Source RG Behavioural Biology, Central Institute of Mental Health, Mannheim, University of Heidelberg, Germany. benedikt.roemer@zi-mannheim.de … Continue reading

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Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial.

Phytother Res. 2013 Jul 6. doi: 10.1002/ptr.5025. [Epub ahead of print] Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial. Sanmukhani J, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB. … Continue reading

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Job creation (paying jobs, that is) anyone? Suicide Among Adults Aged 35–64 Years — United States, 1999–2010

Job creation (paying jobs, that is) anyone? From the CDC: Suicide Among Adults Aged 35–64 Years — United States, 1999–2010. Suicide Among Adults Aged 35–64 Years — United States, 1999–2010 Weekly May 3, 2013 / 62(17);321-325 Suicide is an increasing … Continue reading

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Late-life depression is associated with an increased risk for all-cause dementia.

Review article Late-life depression and risk of vascular dementia and Alzheimer’s disease: systematic review and meta-analysis of community-based cohort studies Breno S. Diniz, Meryl A. Butters, Steven M. Albert, Mary Amanda Dew and Charles F. Reynolds 3rd + Author Affiliations … Continue reading

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Adults with depression and who take specific anti-depressants more likely to develop C. difficile

Interesting applied psychoimmunology study. Apparently depressed people’s guts don’t watch direct-to-consumer chemical-imbalance ads. Here is the abstract. Depression, antidepressant medications, and risk of Clostridium difficile infection Mary A M Rogers1*, M Todd Greene1, Vincent B Young1, Sanjay Saint1,2, Kenneth M … Continue reading

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