Association of Seafood Consumption, Brain Mercury Level, and APOE ε4 Status With Brain Neuropathology in Older Adults

Posted on February 3, 2016 by Maurice Preter MD

Association of Seafood Consumption, Brain Mercury Level, and APOE ε4 Status With Brain Neuropathology in Older Adults Martha Clare Morris, ScD1; John Brockman, PhD2; Julie A. Schneider, MD, MPH3,4,5; Yamin Wang, PhD1; David A. Bennett, MD3,4; Christy C. Tangney, PhD6; Ondine van de Rest, PhD7   [+] Author Affiliations JAMA. 2016;315(5):489-497. doi:10.1001/jama.2015.19451. Importance  Seafood … Continue reading →

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Overprescribing Anticholinergics May Hurt Recovery in Elderly

Posted on February 1, 2016 by Maurice Preter MD

Overprescribing Anticholinergics May Hurt Recovery in Elderly http://news.psu.edu/story/389729/2016/01/28/research/anticholinergics-may-not-be-best-choice-rehab-patients-dementia UNIVERSITY PARK, Pa. — During rehabilitation following an acute hospital stay, medications that block neurotransmitters may be overprescribed to older patients suffering from delirium superimposed on dementia, according to health researchers. Specifically, … Continue reading →

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Quetiapine safety in older adults?

Posted on January 31, 2016 by Maurice Preter MD

Quetiapine safety in older adults? Journal of Clinical Pharmacy and Therapeutics Volume 41,  Issue 1, pages 7–18, February 2016 http://onlinelibrary.wiley.com/doi/10.1111/jcpt.12357/abstract Abstract WHAT IS KNOWN AND OBJECTIVE: Quetiapine is a second-generation antipsychotic that is commonly prescribed for a range of approved and off-label indications … Continue reading →

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A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer’s disease

Posted on January 15, 2016 by Maurice Preter MD

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer’s disease http://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-28 Ingrid Van der Auwera, Stefaan Wera, Fred Van Leuven et al. Nutrition & Metabolism20052:28 Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that primarily … Continue reading →

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Neuroprotective and disease-modifying effects of the ketogenic diet

Posted on January 15, 2016 by Maurice Preter MD

Neuroprotective and disease-modifying effects of the ketogenic diet Behav Pharmacol. Author manuscript; available in PMC 2008 May 5.   Published in final edited form as: Behav Pharmacol. 2006 Sep; 17(5-6): 431–439.   Reading it again.. Well worth it. Abstract The … Continue reading →

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