Arthritis and suicide attempts: findings from a large nationally representative Canadian survey

Posted on July 8, 2016 by Maurice Preter MD

Arthritis and suicide attempts: findings from a large nationally representative Canadian survey The objectives of this study were (1) to determine the odds of suicide attempts among those with arthritis compared with those without and to see what factors attenuate … Continue reading →

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Can Vitamin D Benefit Patients with Prediabetes?

Posted on February 1, 2016 by Maurice Preter MD

  Can Vitamin D Benefit Patients with Prediabetes? No Effect of High-Dose Vitamin D Treatment on β-Cell Function, Insulin Sensitivity, or Glucose Homeostasis in Subjects With Abnormal Glucose Tolerance: A Randomized Clinical Trial Henrik Wagner1⇑, Michael Alvarsson1, Buster Mannheimer2, Marie Degerblad1 and Claes Göran … Continue reading →

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True Risk of Serious Harms with Antidepressants Still Uncertain

Posted on January 31, 2016 by Maurice Preter MD

True Risk of Serious Harms with Antidepressants Still Uncertain http://www.bmj.com/content/352/bmj.i65 Abstract Objective To study serious harms associated with selective serotonin and serotonin-norepinephrine reuptake inhibitors. Design Systematic review and meta-analysis. Main outcome measures Mortality and suicidality. Secondary outcomes were aggressive behaviour and akathisia. Data … Continue reading →

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Quetiapine safety in older adults?

Posted on January 31, 2016 by Maurice Preter MD

Quetiapine safety in older adults? Journal of Clinical Pharmacy and Therapeutics Volume 41,  Issue 1, pages 7–18, February 2016 http://onlinelibrary.wiley.com/doi/10.1111/jcpt.12357/abstract Abstract WHAT IS KNOWN AND OBJECTIVE: Quetiapine is a second-generation antipsychotic that is commonly prescribed for a range of approved and off-label indications … Continue reading →

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Severe parkinsonism due to Reglan (metoclopramide): the importance of early recognition.

Posted on January 15, 2016 by Maurice Preter MD

A reminder.. The well-established but under-appreciated dopamine-blocking effect of metoclopramide. Ned Tijdschr Geneeskd. 2013;157(26):A6037. Severe parkinsonism due to Reglan (metoclopramide): the importance of early recognition. [Article in Dutch] de Ronde MW1, Kingma HJ, Munts AG. Author information 1Kennemer Gasthuis, afd. Neurologie, Haarlem, … Continue reading →

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