Benzodiazepine use and risk of Alzheimer’s disease

Posted on October 10, 2015 by Maurice Preter MD

Benzodiazepine use is associated with an increased risk of Alzheimer’s disease. The stronger association observed for long term exposures reinforces the suspicion of a possible direct association, even if benzodiazepine use might also be an early marker of a condition associated with an increased risk of dementia. Unwarranted long term use of these drugs should be considered as a public health concern. Continue reading →

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Benzodiazepine use associated with increased risk of dementia.

Posted on October 10, 2015 by Maurice Preter MD

Conclusions In this prospective population based study, new use of benzodiazepines was associated with increased risk of dementia. The result was robust in pooled analyses across cohorts of new users of benzodiazepines throughout the study and in a complementary case-control study. Considering the extent to which benzodiazepines are prescribed and the number of potential adverse effects of this drug class in the general population, indiscriminate widespread use should be cautioned against. Continue reading →

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Risk factors for progression of brain atrophy in aging: six-year follow-up of normal subjects.

Posted on June 26, 2015 by Maurice Preter MD

Neurology. 2005 May 24;64(10):1704-11. Risk factors for progression of brain atrophy in aging: six-year follow-up of normal subjects. Enzinger C1, Fazekas F, Matthews PM, Ropele S, Schmidt H, Smith S, Schmidt R. Author information Abstract OBJECTIVES: To determine the rate of brain atrophy in neurologically asymptomatic elderly … Continue reading →

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Hyperglycemia is associated with subtle brain injury and impaired attention and memory even in young adults

Posted on June 26, 2015 by Maurice Preter MD

Neurology. 2015 Jun 9;84(23):2329-37. doi: 10.1212/WNL.0000000000001655. Epub 2015 May 6. Glucose indices are associated with cognitive and structural brain measures in young adults. Weinstein G1, Maillard P2, Himali JJ2, Beiser AS2, Au R2, Wolf PA2, Seshadri S2, DeCarli C2. Author information Abstract OBJECTIVE: To evaluate the possible early … Continue reading →

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Association between benzodiazepine use and occurrence of benign brain tumors.

Posted on June 26, 2015 by Maurice Preter MD

J Neurol Sci. 2014 Jan 15;336(1-2):8-12. doi: 10.1016/j.jns.2013.11.009. Epub 2013 Nov 16. An association between benzodiazepine use and occurrence of benign brain tumors. Harnod T1, Lin CL2, Sung FC2, Kao CH3. Author information Abstract OBJECTIVE: This study was designed to evaluate the impact of long-term … Continue reading →

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