Quetiapine safety in older adults?

Posted on January 31, 2016 by Maurice Preter MD

Quetiapine safety in older adults? Journal of Clinical Pharmacy and Therapeutics Volume 41,  Issue 1, pages 7–18, February 2016 http://onlinelibrary.wiley.com/doi/10.1111/jcpt.12357/abstract Abstract WHAT IS KNOWN AND OBJECTIVE: Quetiapine is a second-generation antipsychotic that is commonly prescribed for a range of approved and off-label indications … Continue reading →

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Severe parkinsonism due to Reglan (metoclopramide): the importance of early recognition.

Posted on January 15, 2016 by Maurice Preter MD

A reminder.. The well-established but under-appreciated dopamine-blocking effect of metoclopramide. Ned Tijdschr Geneeskd. 2013;157(26):A6037. Severe parkinsonism due to Reglan (metoclopramide): the importance of early recognition. [Article in Dutch] de Ronde MW1, Kingma HJ, Munts AG. Author information 1Kennemer Gasthuis, afd. Neurologie, Haarlem, … Continue reading →

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Risk of major cardiac malformations associated with paroxetine use during the first trimester of pregnancy

Posted on January 15, 2016 by Maurice Preter MD

The risk of major cardiac malformations associated with paroxetine use during the first trimester of pregnancy: A systematic review and meta-analysis     http://onlinelibrary.wiley.com/doi/10.1111/bcp.12849/abstract Anick Bérard1,2,*, Noha Iessa1,2, Sonia Chaabane1,2, Flory T. Muanda1,2, Takoua Boukhris1,2 and Jin-Ping Zhao1,2 DOI: 10.1111/bcp.12849 This article … Continue reading →

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Meta-analyses with industry involvement are massively published and report no caveats for antidepressants.

Posted on November 26, 2015 by Maurice Preter MD

CONCLUSION:

There is a massive production of meta-analyses of antidepressants for depression authored by or linked to the industry, and they almost never report any caveats about antidepressants in their abstracts. Our findings add a note of caution for meta-analyses with ties to the manufacturers of the assessed products. Continue reading →

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Serotonin and the marketing of a depression myth

Posted on October 10, 2015 by Maurice Preter MD

Serotonin and the marketing of a depression myth Serotonin and depression BMJ 2015; 350 doi: http://dx.doi.org.ezproxy.cul.columbia.edu/10.1136/bmj.h1771 (Published 21 April 2015)Cite this as: BMJ 2015;350:h1771  Article Related content Metrics Responses David Healy, professor of psychiatry Author affiliations david.healy54@googlemail.com The marketing of a myth The serotonin reuptake inhibiting … Continue reading →

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