Using LED strobe lights to potentially treat Alzheimer’s disease by clearing amyloid plaques in the brain

Using LED strobe lights to potentially treat Alzheimer’s disease by clearing amyloid plaques in the brain ## The Discovery In 2016, researchers at MIT led by Dr. Li-Huei Tsai found that exposing mice to LED lights flickering at 40 hertz … Continue reading

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Lung Microbiota: Its Relationship to Respiratory System Diseases and Approaches for Lung-Targeted Probiotic Bacteria Delivery

Really interesting topic and paper (well illustrated too). Eat more kimchi! Source: https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.3c00323 Abstract Microorganisms that make up the local microbiota (such as Lactobacillus sp. and Bifidobacteriumsp.) play a crucial role in the modulation of diseases and health states by … Continue reading

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‘On-Demand’ Fast Mobilizes Fat; Low-Carb Breakfast Stymies Hunger – Medscape – Oct 12, 2020.

‘On-Demand’ Fast Mobilizes Fat; Low-Carb Breakfast Stymies Hunger – Medscape – Oct 12, 2020.   ‘On-Demand’ Fast Mobilizes Fat; Low-Carb Breakfast Stymies Hunger Becky McCall October 12, 2020 Greater fat tissue mobilization can be achieved through early-day fasting in comparison to consuming a low-carbohydrate breakfast or a Mediterranean-style … Continue reading

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Feeling dead tired? Scientists may finally be on the verge of learning why too little sleep is inevitably fatal.

Inside a series of tubes in a bright, warm room at Harvard Medical School, hundreds of fruit flies are staying up late. It has been days since any of them have slept: The constant vibrations that shake their homes preclude rest, cling as they might to the caps of the tubes for respite. Not too far away in their own tubes live other sleepless flies, animated with the calm persistence of those consigned to eternal day. A genetic tweak to certain neurons in their brains keeps them awake for as long as they live. Continue reading

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Efficacy and Safety of Tremella fuciformis in Individuals with Subjective Cognitive Impairment: A Randomized Controlled Trial

The efficacy and safety of Tremella fuciformis (TF) as a nutritional supplement were assessed in individuals with subjective cognitive impairment (SCI). Seventy-five individuals with SCI were enrolled in an 8-week, randomized, double-blind, placebo-controlled trial of TF (600 mg/day, n = 30 or 1200 mg/day, n = 30) or placebo (n = 15). The primary outcome measure was changes in total scores of the subjective memory complaint questionnaire. The secondary outcome measures were changes in performance on short-term memory and executive functions, which were assessed using standardized cognitive tests. In addition, voxel-based morphometry was performed to examine the effects of TF on changes in gray matter volume. The individuals in the TF group showed greater improvements in the total scores on the subjective memory complaint questionnaire compared with those in the placebo group. There were also significantly greater improvements in short-term memory and executive functions in the TF group relative to the placebo group. Exploratory analysis demonstrated that there were significant group-by-visit interactions on the left precuneus, right supramarginal gyrus, right middle frontal gyrus, and right postcentral gyrus at corrected P < .05. Overall frequency of adverse events did not differ among high-dose TF (40.4%), low-dose TF (35.1%), and placebo groups (41.4%). The current findings suggest that TF could be safely administered to relieve subjective memory complaints and enhance cognition in individuals with SCI. Continue reading

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