Rhodiola rosea L. and Alzheimer’s Disease: From Farm to Pharmacy

A plethora of studies report that R. rosea has potent neuroprotective effects through the suppression of oxidative stress, neuroinflammation, and excitotoxicity in brain tissues and antagonism of oncogenic p21-activated kinase. However, to our knowledge, no review articles have been published addressing the neuroprotective effects of R. rosea. Continue reading

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Current low to moderate alcohol consumption among middle-aged or older adults may be associated with better total cognitive function.

Current low to moderate alcohol consumption among middle-aged or older adults may be associated with better total cognitive function. Continue reading

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The passage of time during the UK Covid-19 lockdown

Abstract

In March 2020, in response to the Covid-19 pandemic, the UK Government imposed social and physical distancing measures on the population. These lockdown measures caused significant changes to all aspects of daily life. The current study examined how the passage of time was distorted during the lockdown period. Using an online questionnaire, day and week passage of time judgments were collected. In addition, measures of affect, task load and satisfaction with current levels of social interaction were taken. The results show that over 80% of participants experienced distortion to the passage of time during lockdown in comparison with normal. The passage of time during the day was predicted by age, stress, task load and satisfaction with current levels of social interaction. A slowing of the passage of time was associated with increasing age, increasing stress, reduced task load and reduced satisfaction with current levels of social interaction. Only age and satisfaction with current levels of social interaction predicted passage of time across a week. Again, increasing age and reduced satisfaction with levels of social interaction were associated with a slowing of the passage of time. These findings demonstrate that significant changes to daily life have a significant impact on our experience of time, with younger, more socially satisfied people more likely to experience time as passing more quickly during the lockdown. Continue reading

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Belly fat in older women is linked to a 39% higher risk of dementia within 15 years, study says

Probably not just in older women? https://www.cnn.com/2020/06/23/health/belly-fat-dementia-link-wellness/index.html (CNN)For older adults, your current belly size could be a key indicator in whether you develop dementia within the next decade or two. For women that risk is particularly high. For women in … Continue reading

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Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

Review  Volume 179, Issue 2, pp. 312-339, October 3, 2019 Justin M. Long David M. Holtzman References Article Info Published: September 26, 2019DOI:https://doi.org/10.1016/j.cell.2019.09.001 Alzheimer disease (AD) is a heterogeneous disease with a complex pathobiology. The presence of extracellular β-amyloid deposition … Continue reading

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