Phosphodiesterase Type 5 Inhibitors in Men With Erectile Dysfunction and the Risk of Alzheimer Disease

A typical silly research paper title:

The point the authors are making is sildefanil and such compounds (ViagraR etc.) may be protective against Alzheimer Disease-type neurodegeneration. Or is it that the desire for, and frequency of intercourse are protective? 

Source: https://www.neurology.org/doi/full/10.1212/WNL.0000000000209131

Either way, this is one of the more interesting drug explorations in the world of “dementia drugs”. And repurposing a compound adds years of post-marketing surveillance.

 

 

 

 

 

Maurice Preter, MD

About Maurice Preter MD

Maurice Preter, MD is a European and U.S. educated psychiatrist, psychotherapist, psychopharmacologist, neurologist, and medical-legal expert in private practice in Manhattan. He is also the principal of Fifth Avenue Concierge Medicine, PLLC, a medical concierge service and health advisory for select individuals and families.
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