Bryan Johnson, the 47-year-old tech entrepreneur known for his extreme anti-aging efforts, has recently discontinued his use of rapamycin, a drug he had been taking for nearly five years as part of his longevity regimen[2][8]. This decision has sparked renewed discussion about the potential risks and benefits of using drugs like rapamycin for anti-aging purposes.

Posted on January 16, 2025 by Maurice Preter MD

Bryan Johnson, the 47-year-old tech entrepreneur known for his extreme anti-aging efforts, has recently discontinued his use of rapamycin, a drug he had been taking for nearly five years as part of his longevity regimen. This decision has sparked renewed … Continue reading →

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Tamsulosin and the risk of dementia in older men with benign prostatic hyperplasia

Posted on December 8, 2020 by Maurice Preter MD

  Comparative Study   Pharmacoepidemiol Drug Saf   2018 Mar;27(3):340-348.  doi: 10.1002/pds.4361. Epub 2018 Jan 9. Tamsulosin and the risk of dementia in older men with benign prostatic hyperplasia   Yinghui Duan 1 2, James J Grady 1 2, Peter C Albertsen 3, Z Helen Wu 2 4 Affiliations expand PMID: 29316005   … Continue reading →

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Metformin Use Is Associated With Slowed Cognitive Decline and Reduced Incident Dementia in Older Adults With Type 2 Diabetes

Posted on October 11, 2020 by Maurice Preter MD

Metformin Use Is Associated With Slowed Cognitive Decline and Reduced Incident Dementia in Older Adults With Type 2 Diabetes: The Sydney Memory and Ageing Study Katherine Samaras, Steve Makkar, John D. Crawford, Nicole A. Kochan, Wei Wen, Brian Draper, Julian … Continue reading →

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Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

Posted on November 4, 2019 by Maurice Preter MD

Review  Volume 179, Issue 2, pp. 312-339, October 3, 2019 Justin M. Long David M. Holtzman References Article Info Published: September 26, 2019DOI:https://doi.org/10.1016/j.cell.2019.09.001 Alzheimer disease (AD) is a heterogeneous disease with a complex pathobiology. The presence of extracellular β-amyloid deposition … Continue reading →

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Alzheimer’s Drug Linked to Potentially Serious Muscle Condition

Posted on November 4, 2019 by Maurice Preter MD

  Megan Brooks September 19, 2019 The Alzheimer’s drug donepezil (multiple brands) is associated with a twofold higher risk for hospital admission for rhabdomyolysis, a rare but potentially life-threatening condition in which muscle cells break down. It can lead to kidney damage. … Continue reading →

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